Development of a mini-phototest method for precision phototherapy

Giselle Tian; Zhenguo Wu; Jianhua Zhao; Harvey Lui; Sunil Kalia; Haishan Zeng

doi:10.1117/12.3009063

13 March 2024 Development of a mini-phototest method for precision phototherapy

Giselle Tian, Zhenguo Wu, Jianhua Zhao, Harvey Lui, Sunil Kalia, Haishan Zeng

Proceedings Volume PC12816, Photonics in Dermatology and Plastic Surgery 2024; PC128160D (2024) https://doi.org/10.1117/12.3009063
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

We introduce a “mini-phototest” concept, which reduces the skin area exposed to UV light by 20-folds for skin MED (minimal erythema dose) determination. This significantly minimizes cosmetic effects compared to conventional phototest. We validated this concept by Monte-Carlo simulation, and also studied cellular response induced by mini-size UV exposure using in vivo multimodality microscopy. This novel phototest method may enable site specific light dosimetry, facilitating personalized precision phototherapy.

Conference Presentation

Citation Download Citation

Giselle Tian, Zhenguo Wu, Jianhua Zhao, Harvey Lui, Sunil Kalia, and Haishan Zeng "Development of a mini-phototest method for precision phototherapy", Proc. SPIE PC12816, Photonics in Dermatology and Plastic Surgery 2024, PC128160D (13 March 2024); https://doi.org/10.1117/12.3009063

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