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We present photoacoustic computed tomography through an ergodic relay (PACTER), a method for single-shot 3D imaging of hemodynamics using a single-element detector. Our approach allows for ultrafast volumetric imaging at kilohertz rates without the need for numerous detector elements. We demonstrate PACTER in both human and small animal subjects, emphasizing its potential utility in early detection and monitoring of peripheral vascular diseases. Our single-element detector design aims to offer a more convenient and potentially affordable option, while the concept could also be relevant to other imaging technologies, contributing to various applications in medical imaging.
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Yide Zhang, Peng Hu, Lei Li, Rui Cao, Anjul Khadria, Konstantin Maslov, Xin Tong, Yushun Zeng, Laiming Jiang, Qifa Zhou, Lihong V. Wang, "Ultrafast single-shot 3D photoacoustic tomography in vivo using a single-element detector," Proc. SPIE PC12842, Photons Plus Ultrasound: Imaging and Sensing 2024, PC128420I (13 March 2024); https://doi.org/10.1117/12.3007503