Multimodal SWIR Laser Imaging for Assessment and Detection of Urothelial Carcinomas

Castro-Olvera, Gustavo, ICFO - Institut de Ciències Fotòniques; Morselli, Simone, Azienda Ospedaliera Univ. Careggi; Gacci, Mauro, Univ. Hospital Careggi; Serni, Sergio, Univ. Hospital Careggi; Liaci, Andrea, Univ. degli Studi di Firenze; Nicoletti, Rossella, Univ. Cattolica del Sacro Cuore; Loza-Alvarez, Pablo, ICFO - Institut de Ciències Fotòniques

doi:10.1117/3.2604326.ch8

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Multimodal SWIR Laser Imaging for Assessment and Detection of Urothelial Carcinomas

Book: Short-Wavelength Infrared Windows for Biomedical Applications

Editor(s): Laura A. Sordillo; Peter P. Sordillo

Author(s): Gustavo Castro-Olvera, Simone Morselli, Mauro Gacci, Sergio Serni, Andrea Liaci, Rossella Nicoletti, Pablo Loza-Alvarez

Published: 2021

https://doi.org/10.1117/3.2604326.ch8

Author Affiliations +

Abstract

Urothelial carcinomas (UCs) represent the fourth most common tumor type in developed countries; UCs can be further divided into lower (bladder and urethra) or upper (pyelocaliceal cavities and ureter) urinary tract cancers.1 Among them, bladder cancer (BCa) is the most common urinary tract malignancy worldwide, accounting for up to 95% of UCs. In the European Union, the age-standardized incidence rate of BCa is 19.1 and 4.0 cases per 100,000 person-years for men and women, respectively. However, upper urinary tract urothelial carcinomas (UTUCs) are relatively uncommon and account only for 5% to 10% of UCs, with an estimated annual incidence in Western countries of almost 2 cases per 100,000 person-years. Globally, UC incidence and mortality rates vary across different countries due to differences in risk factors, diagnostic practices, and availability of treatments.