Integrated autofluorescence endoscopic imaging and point-wise spectroscopy for real-time in vivo tissue measurements

Kan Lin; Wei Zheng; Zhiwei Huang

doi:10.1117/1.3475955

1 July 2010 Integrated autofluorescence endoscopic imaging and point-wise spectroscopy for real-time in vivo tissue measurements

Kan Lin, Wei Zheng, Zhiwei Huang

Author Affiliations +

Journal of Biomedical Optics, Vol. 15, Issue 4, 040507 (July 2010). https://doi.org/10.1117/1.3475955

Abstract

We report on the development of an integrated point-wise spectroscopy and autofluorescence (AF) endoscopic imaging technique for real-time in vivo tissue measurements at endoscopy. We implement a unique point spectrum optical design to realize real-time AF imaging and AF or diffuse reflectance (DR) spectroscopy measurements from a small area of tissue of interest on the AF image. We demonstrate that both the AF image and the point-wise AF/DR spectra can be simultaneously acquired from the oral cavity in vivo within 0.1 s, suggesting the potential of the integrated spectroscopy and endoscopic imaging technique developed to facilitate in vivo tissue diagnosis and characterization at endoscopy.

©(2010) Society of Photo-Optical Instrumentation Engineers (SPIE)

Citation Download Citation

Kan Lin, Wei Zheng, and Zhiwei Huang "Integrated autofluorescence endoscopic imaging and point-wise spectroscopy for real-time in vivo tissue measurements," Journal of Biomedical Optics 15(4), 040507 (1 July 2010). https://doi.org/10.1117/1.3475955

Published: 1 July 2010

ACCESS THE FULL ARTICLE

JOURNAL ARTICLE
3 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY