Open Access
3 December 2012 Three-dimensional imaging of normal skin and nonmelanoma skin cancer with cellular resolution using Gabor domain optical coherence microscopy
Kye-Sung Lee, Huimin Zhao, Sherrif F. Ibrahim, Natthani Meemon, Laura Khoudeir, Jannick P. Rolland
Author Affiliations +
Abstract
We investigate morphological differences in three-dimensional (3-D) images with cellular resolution between nonmelanoma skin cancer and normal skin using Gabor domain optical coherence microscopy. As a result, we show for the first time cellular optical coherence images of 3-D features differentiating cancerous skin from normal skin. In addition, in vivo volumetric images of normal skin from different anatomic locations are shown and compared.
© 2012 Society of Photo-Optical Instrumentation Engineers (SPIE) 0091-3286/2012/$25.00 © 2012 SPIE
Kye-Sung Lee, Huimin Zhao, Sherrif F. Ibrahim, Natthani Meemon, Laura Khoudeir, and Jannick P. Rolland "Three-dimensional imaging of normal skin and nonmelanoma skin cancer with cellular resolution using Gabor domain optical coherence microscopy," Journal of Biomedical Optics 17(12), 126006 (3 December 2012). https://doi.org/10.1117/1.JBO.17.12.126006
Published: 3 December 2012
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CITATIONS
Cited by 46 scholarly publications.
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KEYWORDS
Skin

3D image processing

Image resolution

In vivo imaging

Optical coherence tomography

Skin cancer

Tissue optics

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