CONFERENCE PROCEEDINGS
Advanced Search
Home > Journals > J. Biomed. Opt. > Volume 20 > Issue 1 > Article
Open Access
20 January 2015 Image overlay solution based on threshold detection for a compact near infrared fluorescence goggle system
Shengkui Gao, Suman B. Mondal, Nan Zhu, RongGuang Liang, Samuel Achilefu, Viktor Gruev
Author Affiliations +
Journal of Biomedical Optics, Vol. 20, Issue 1, 016018 (January 2015). https://doi.org/10.1117/1.JBO.20.1.016018
Abstract
Near infrared (NIR) fluorescence imaging has shown great potential for various clinical procedures, including intraoperative image guidance. However, existing NIR fluorescence imaging systems either have a large footprint or are handheld, which limits their usage in intraoperative applications. We present a compact NIR fluorescence imaging system (NFIS) with an image overlay solution based on threshold detection, which can be easily integrated with a goggle display system for intraoperative guidance. The proposed NFIS achieves compactness, light weight, hands-free operation, high-precision superimposition, and a real-time frame rate. In addition, the miniature and ultra-lightweight light-emitting diode tracking pod is easy to incorporate with NIR fluorescence imaging. Based on experimental evaluation, the proposed NFIS solution has a lower detection limit of 25 nM of indocyanine green at 27 fps and realizes a highly precise image overlay of NIR and visible images of mice in vivo. The overlay error is limited within a 2-mm scale at a 65-cm working distance, which is highly reliable for clinical study and surgical use.
© 2015 Society of Photo-Optical Instrumentation Engineers (SPIE) 0091-3286/2015/$25.00 © 2015 SPIE
Citation Download Citation
Shengkui Gao, Suman B. Mondal, Nan Zhu, RongGuang Liang, Samuel Achilefu, and Viktor Gruev "Image overlay solution based on threshold detection for a compact near infrared fluorescence goggle system," Journal of Biomedical Optics 20(1), 016018 (20 January 2015). https://doi.org/10.1117/1.JBO.20.1.016018
Published: 20 January 2015
JOURNAL ARTICLE
 9 PAGES
DOWNLOAD PAPER SAVE TO MY LIBRARY
GET CITATION
Lens.org Logo
CITATIONS
Cited by 12 scholarly publications.
Advertisement
Advertisement
RIGHTS & PERMISSIONS
Get copyright permission  Get copyright permission on Copyright Marketplace
KEYWORDS
Near infrared
Imaging systems
Luminescence
Light emitting diodes
Visible radiation
Goggles
Optical sensors
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top