Characterization of anisotropy of elastic modulus with three-dimensional freehand scan shear wave elasticity imaging

Tong Wu; En-Xiang Shen; Zhi-Bin Jin; Yong Jiang; Ying Chen; Chao Tao; Jie Yuan; Yun Ge; Xiao-Jun Liu

doi:10.1117/1.JMI.10.6.066002

17 November 2023 Characterization of anisotropy of elastic modulus with three-dimensional freehand scan shear wave elasticity imaging

Tong Wu, En-Xiang Shen, Zhi-Bin Jin, Yong Jiang, Ying Chen, Chao Tao, Jie Yuan, Yun Ge, Xiao-Jun Liu

Author Affiliations +

Journal of Medical Imaging, Vol. 10, Issue 6, 066002 (November 2023). https://doi.org/10.1117/1.JMI.10.6.066002

Abstract

Purpose

The purpose of this study is to develop a freehand scan three-dimensional (3D) shear wave elasticity imaging (SWEI) method for characterizing the anisotropy of elastic properties in biological tissues. The motivation behind this work lies in addressing the limitations of traditional two-dimensional (2D) SWEI, which only measures shear wave speeds in a single direction, as well as fulfilling the clinical demand for improved medical imaging.

Approach

Our imaging system utilizes a high-definition optical camera to continuously track the ultrasonic transducer, collecting spatial position-angle data of the transducer and corresponding two-dimensional SWEI data. By reconstructing three-dimensional SWEI images using these data, we achieved freehand SWEI.

Results

We validated the accuracy of 2D SWEI on a standard elastic phantom, and then performed 3D SWEI on the pork tenderloin and the triceps brachii of two volunteers. We obtained shear wave speed of 1.82 to 3.12 m / s in the pork tenderloin, shear wave speed of 1.16 to 2.36 m / s in the triceps brachii of non-exercising volunteers, and shear wave speed of 0.55 to 1.63 m / s in the triceps brachii of exercising volunteers, and the maximum shear wave speed directions were generally aligned with the orientation of muscle fibers.

Conclusions

We proposed a method that can overcome the limitations of 2D-SWEI regarding imaging angle while also extending the imaging angle of 3D-SWEI, which could have significant implications for improving the accuracy and safety of medical diagnoses.

Citation Download Citation

Tong Wu, En-Xiang Shen, Zhi-Bin Jin, Yong Jiang, Ying Chen, Chao Tao, Jie Yuan, Yun Ge, and Xiao-Jun Liu "Characterization of anisotropy of elastic modulus with three-dimensional freehand scan shear wave elasticity imaging," Journal of Medical Imaging 10(6), 066002 (17 November 2023). https://doi.org/10.1117/1.JMI.10.6.066002

Received: 15 May 2023; Accepted: 6 November 2023; Published: 17 November 2023

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KEYWORDS

Tissues

Cameras

Anisotropy

Calibration

Elastic modulus

Elasticity

Ultrasonics

Purpose

Approach

Results

Conclusions

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