Prof. Alberto D. Dalla Mora Profile

Prof. Alberto D. Dalla Mora

Associate Professor at Politecnico di Milano

SPIE Involvement:

Author

Area of Expertise:

Photon Migration , Single-Photon Detectors , Single-Photon Avalanche Diodes , Time-Domain Diffuse Optics , Silicon Photomultipliers , Time-Correlated Single-Photon Counting

Websites:

Personal Website | Company Website

Profile Summary

Alberto Dalla Mora received the master degree summa cum laude in Electronics Engineering and the Ph.D. degree summa cum laude in Information and Communication Technology from Politecnico di Milano (Milan, Italy) in 2006 and 2010, respectively. In 2010 he was awarded the Dimitris N. Chorafas Foundation Prize for exceptional doctoral research projects. He has been an Assistant Professor of Physics at Politecnico di Milano between 2011 and 2018. He is currently an associate professor at the Physics Department of Politecnico di Milano. His research activity is focused on time-resolved diffuse spectroscopy instrumentations and applications for biomedical diagnosis. He designed, developed and characterized different innovative building blocks for diffuse optics systems, also developing novel approaches to photon migration like the null source-detector separation technique by means of fast-gated Single-Photon Avalanche Diodes. He co-authored more than 180 scientific publications.

Publications (88)

Proceedings Article | 8 September 2023 Paper

Paper

Use of bioresorbable fibers for interstitial time-domain diffuse optical spectroscopy with fast-gating

Vamshi Damagatla, Nadia Boetti, Laura Di Sieno, Diego Pugliese, Davide Janner, Alberto Dalla Mora, Antonio Pifferi

Proceedings Volume 12628, 1262818 (2023) https://doi.org/10.1117/12.2670504

KEYWORDS: Absorption, Diffuse optical spectroscopy, Single photon avalanche diodes, Scattering, Liquids, Tissues, Optical fibers, Light scattering, Glasses, Water

Read Abstract +

Proceedings Article | 9 August 2023 Paper

Paper

Towards time-domain diffuse optics with extreme photon rate

L. Di Sieno, T. Talala, E. Avanzi, I. Nissinen, J. Nissinen, A. Dalla Mora

Proceedings Volume 12628, 1262815 (2023) https://doi.org/10.1117/12.2669264

KEYWORDS: Diffuse optical imaging, Pulsed laser operation, Photon counting, Mammography, Light harvesting, Integrated optics, In vivo imaging, Heart, Equipment, Distortion

Read Abstract +

Proceedings Article | 9 August 2023 Paper

Paper

Initial examples of the SOLUS multimodal potential

G. Maffeis, A. Pifferi, A. Dalla Mora, L. Di Sieno, R. Cubeddu, A. Tosi, E. Conca, A. Giudice, A. Ruggeri, S. Tisa, A. Flocke, B. Rosinski, J.-M. Dinten, M. Perriollat, C. Fraschini, J. Lavaud, S. Arridge, G. Di Sciacca, A. Farina, P. Panizza, E. Venturini, P. Gordebeke, P. Taroni

Proceedings Volume 12628, 1262807 (2023) https://doi.org/10.1117/12.2670430

KEYWORDS: Radio optics, Machine learning, Data processing, Absorption, Ultrasonography, Multimodal imaging, Elastography, Doppler tomography, Diffuse optical tomography, Critical dimension metrology

Read Abstract +

Proceedings Article | 7 March 2023 Presentation + Paper

Presentation + Paper

Breast lesion classification based on absorption and composition parameters: a look at SOLUS first outcomes

G. Maffeis, A. Pifferi, A. Dalla Mora, L. Di Sieno, R. Cubeddu, A. Tosi, E. Conca, A. Giudice, A. Ruggeri, S. Tisa, A. Flocke, B. Rosinski, J.-M Dinten, M. Perriollat, C. Fraschini, J. Lavaud, S. Arridge, G. Di Sciacca, A. Farina, P. Panizza, E. Venturini, P. Gordebeke, Paola Taroni

Proceedings Volume 12376, 123760K (2023) https://doi.org/10.1117/12.2648945

KEYWORDS: Breast, Absorption, Machine learning, Image segmentation, Diffuse optical tomography, Diffuse optical imaging, Data analysis, Breast cancer, Ultrasound transducers

Read Abstract +

Proceedings Article | 7 March 2023 Presentation + Paper

Presentation + Paper

Evaluation of the timing performance of silicon photomultiplier detectors array and its preliminary application in fluorescence lifetime sensing and diffuse optics

E. Avanzi, A. Ghezzi, A. Farina, C. D'Andrea, A. Dalla Mora, L. Di Sieno

Proceedings Volume 12376, 123760N (2023) https://doi.org/10.1117/12.2648786

KEYWORDS: Fluorescence, Silicon photomultipliers, Prototyping, Detector arrays, Signal detection, Single photon detectors, Picosecond phenomena, Diffuse optical imaging, Absorption, Time correlated single photon counting

Read Abstract +

SPIE Journal Paper | 15 June 2022 Open Access

Open Access

Multi-laboratory performance assessment of diffuse optics instruments: the BitMap exercise

Pranav Lanka, Lin Yang, David Orive-Miguel, Joshua Deepak Veesa, Susanna Tagliabue, Aleh Sudakou, Saeed Samaei, Mario Forcione, Zuzana Kovacsova, Anurag Behera, Thomas Gladytz, Dirk Grosenick, Lionel Hervé, Turgut Durduran, Karolina Bejm, Magdalena Morawiec, Michał Kacprzak, Piotr Sawosz, Anna Gerega, Adam Liebert, Antonio Belli, Ilias Tachtsidis, Frédéric Lange, Gemma Bale, Luca Baratelli, Sylvain Gioux, Alexander Kalyanov, Martin Wolf, Sanathana Konugolu-Venkata-Sekar, Marta Zanoletti, Ileana Pirovano, Michele Lacerenza, Lina Qiu, Edoardo Ferocino, Giulia Maffeis, Caterina Amendola, Lorenzo Colombo, Lorenzo Frabasile, Pietro Levoni, Mauro Buttafava, Marco Renna, Laura Di Sieno, Rebecca Re, Andrea Farina, Lorenzo Spinelli, Alberto Dalla Mora, Davide Contini, Paola Taroni, Alberto Tosi, Alessandro Torricelli, Hamid Dehghani, Heidrun Wabnitz, Antonio Pifferi

JBO, Vol. 27, Issue 07, 074716, (June 2022) https://doi.org/10.1117/12.10.1117/1.JBO.27.7.074716

KEYWORDS: Raster graphics, Optical properties, Diffuse optical imaging, Scattering, Imaging spectroscopy, Absorption, Tissue optics, Spectroscopes, Sensors, Oximetry

Read Abstract +

SPIE Journal Paper | 24 March 2022 Open Access

Open Access

Evaluation of a pipeline for simulation, reconstruction, and classification in ultrasound-aided diffuse optical tomography of breast tumors

Giuseppe Di Sciacca, Giulia Maffeis, Andrea Farina, Alberto Dalla Mora, Antonio Pifferi, Paola Taroni, Simon Arridge

JBO, Vol. 27, Issue 03, 036003, (March 2022) https://doi.org/10.1117/12.10.1117/1.JBO.27.3.036003

KEYWORDS: Tissues, Breast, Acoustics, Absorption, Tissue optics, Ultrasonography, Scattering, Image segmentation, Computer simulations, Diffuse optical tomography

Read Abstract +

Proceedings Article | 7 March 2022 Presentation

Presentation

Multimodal hybrid diffuse optics and ultrasound for screening for thyroid cancer

Pablo Fernández Esteberena, Gloria Aranda, Mauro Buttafava, Davide Contini, Lorenzo Cortese, Alberto Dalla Mora, Hamid Dehghani, Sixte de Fraguier, Felicia Hanzu, Giuseppe Lo Presti, Mireia Mora, An Nguyen Dinh, Antonio Pifferi, Marco Renna, Bogdan Rosinsky, Sabina Ruiz Janer, Mattia Squarcia, Paola Taroni, Alberto Tosi, Udo Weigel, Stanislaw Wojtkiewicz, Marta Zanoletti, Lisa Kobayashi Frisk, Turgut Durduran

Proceedings Volume PC11952, PC119520A (2022) https://doi.org/10.1117/12.2608941

KEYWORDS: Cancer, Ultrasonography, Diffuse optical imaging, Oxygen, Imaging systems, Diagnostics, Tumor growth modeling, Tissues, Tissue optics, Time resolved spectroscopy

Read Abstract +

Proceedings Article | 3 March 2022 Paper

Paper

Breaking the rules of time-domain diffuse optics: working with 1 cm2 SiPM and well-beyond the single-photon statistics

L. Di Sieno, E. Avanzi, F. Acerbi, A. Gola, M. Lacerenza, A. Behera, D. Contini, A. Dalla Mora

Proceedings Volume 11974, 119740A (2022) https://doi.org/10.1117/12.2608656

KEYWORDS: Photons, Sensors, Absorption, Microchannel plates, Scattering, Diffuse optical imaging, Chromium, Single photon detectors, Light harvesting, Solids

Read Abstract +

Proceedings Article | 2 March 2022 Presentation + Paper

Presentation + Paper

Performance and reproducibility assessment across multiple time-domain near-infrared spectroscopy device replicas

M. Lacerenza, A. Torricelli, A. Tosi, D. Contini, A. Dalla Mora, A. Pifferi, F. Zappa, M. Buttafava

Proceedings Volume 11951, 1195108 (2022) https://doi.org/10.1117/12.2609404

KEYWORDS: Tissue optics, Near infrared spectroscopy, Picosecond phenomena, Scattering, Photons, Absorption, Manufacturing, Hemodynamics, Tissues, Standards development, Accuracy assessment

Read Abstract +

Proceedings Article | 9 December 2021 Paper

Paper

SOLUS: a novel multimodal approach to ultrasound and diffuse optics imaging of breast cancer

Antonio Pifferi, Alberto Dalla Mora, Laura Di Sieno, Giulia Maffeis, Alberto Tosi, Enrico Conca, Vincenzo Sesta, Andrea Giudice, Alessandro Ruggeri, Simone Tisa, Alexander Flocke, Bogdan Rosinski, Jean-Marc Dinten, Mathieu Perriollat, Hélène Sportouche, Christophe Fraschini, Simon Arridge, Giuseppe Di Sciacca, Andrea Farina, Pietro Panizza, Elena Venturini, Peter Gordebeke, Pamela Zolda, Paola Taroni

Proceedings Volume 11920, 1192003 (2021) https://doi.org/10.1117/12.2614309

KEYWORDS: Tissues, Picosecond phenomena, Imaging systems, Ultrasonography, Diffuse optical imaging, Breast cancer, Mammography, Sensors, Multimodal imaging, Breast

Read Abstract +

Proceedings Article | 9 December 2021 Paper

Paper

Silicon photomultiplier-based detection module with up to 1 cm2 area to push time-domain diffuse optics performances

Laura Di Sieno, Alberto Dalla Mora, Anurag Behera, Alberto Gola, Fabio Acerbi

Proceedings Volume 11920, 1192005 (2021) https://doi.org/10.1117/12.2615204

KEYWORDS: Sensors, Optical properties, In vivo imaging, Diffuse optical imaging, Signal detection, Light harvesting, Absorption, Silicon, Radiography, Radio optics

Read Abstract +

Proceedings Article | 9 December 2021 Paper

Paper

Time-domain diffuse optics beyond pile-up limits: a simulation study based on relevant figures of merit

Elisabetta Avanzi, Laura Di Sieno, Anurag Behera, Davide Contini, Alberto Dalla Mora

Proceedings Volume 11920, 1192006 (2021) https://doi.org/10.1117/12.2615206

KEYWORDS: Chromium, Photons, Scattering, Diffuse optical imaging, Laser scattering, Distortion, Picosecond phenomena, Optical properties, Microchannel plates, Absorption

Read Abstract +

Proceedings Article | 9 December 2021 Paper

Paper

Optical mammography in the time domain up to 1060 nm: from tests on healthy women to initial data for monitoring neoadjuvant chemotherapy

Giulia Maffeis, Edoardo Ferocino, Alberto Dalla Mora, Rinaldo Cubeddu, Antonio Pifferi, Carolina Santangelo, Pietro Panizza, Paola Taroni

Proceedings Volume 11920, 119200O (2021) https://doi.org/10.1117/12.2615236

KEYWORDS: Breast, Tumors, Collagen, Therapeutics, In vivo imaging, Oxygen, Optical testing, Mammography, Clinical trials, Signal processing

Read Abstract +

Proceedings Article | 9 December 2021 Paper

Paper

Fast-gated digital silicon photomultiplier maximizes light harvesting and depth sensitivity in time-domain diffuse optics

Alberto Dalla Mora, Laura Di Sieno, Edoardo Ferocino, Enrico Conca, Vincenzo Sesta, Mauro Buttafava, Federica Villa, Franco Zappa, Davide Contini, Alessandro Torricelli, Paola Taroni, Alberto Tosi, Antonio Pifferi

Proceedings Volume 11920, 1192004 (2021) https://doi.org/10.1117/12.2614311

KEYWORDS: Photons, Light harvesting, Silicon photomultipliers, Diffuse optical imaging, Sensors, In vivo imaging, Digital photography, Optical signal processing, Picosecond phenomena, Tissues

Read Abstract +

Proceedings Article | 9 December 2021 Paper

Paper

Motor cortex hemodynamic response function in freely moving subjects recorded via time domain fNIRS

Michele Lacerenza, Mauro Buttafava, Lorenzo Spinelli, Alberto Tosi, Alberto Dalla Mora, Franco Zappa, Antonio Pifferi, Bruno Cozzi, Alessandro Torricelli, Davide Contini

Proceedings Volume 11920, 1192018 (2021) https://doi.org/10.1117/12.2615350

KEYWORDS: Hemodynamics, Human subjects, Brain activation, Brain, Tissue optics, Solids, Scattering, Near infrared spectroscopy, Laser scattering, Functional magnetic resonance imaging

Read Abstract +

Proceedings Article | 9 December 2021 Paper

Paper

Potential for improved thyroid cancer screening aided by multi-modal clinical ultrasound and hybrid diffuse optics (LUCA platform)

Pablo Fernandez Esteberena, G. Aranda, M. Buttafava, D. Contini, L. Cortese, A. Dalla Mora, H. Dehghani, S. de Fraguier, F. Hanzu, G. Lo Presti, M. Mora Porta, A. Nguyen-Dihn, A. Pifferi, M. Renna, B. Rosinski, S. Ruiz Janer, M. Squarcia, P. Taroni, A. Tosi, U. Weigel, S. Wojtkiewicz, M. Zanoletti, T. Durduran

Proceedings Volume 11920, 119200P (2021) https://doi.org/10.1117/12.2615237

KEYWORDS: Cancer, Ultrasonography, Tumor growth modeling, Tissues, Diffuse optical imaging, Near infrared spectroscopy, Hemodynamics, Neck, Diffusion, Blood circulation

Read Abstract +

Proceedings Article | 5 March 2021 Presentation + Paper

Presentation + Paper

High-throughput multi-wavelength time-resolved optical mammograph: importance of in vivo performance assessment

Giulia Maffeis, Edoardo Ferocino, Alberto Dalla Mora, Rinaldo Cubeddu, Antonio Pifferi, Paola Taroni

Proceedings Volume 11639, 1163908 (2021) https://doi.org/10.1117/12.2577516

KEYWORDS: In vivo imaging, Collagen, Stray light, Silicon photomultipliers, Optical properties, New and emerging technologies, Infrared radiation, Clinical trials, Breast, Absorption

Read Abstract +

Proceedings Article | 5 March 2021 Presentation + Paper

Presentation + Paper

Investigating the lung using time-resolved diffuse optics

Antonio Pifferi, Andrea Farina, Alberto Dalla Mora, Pranav Lanka, Sanathana Konugolu Venkata Sekar, Massimo Miniati, Paola Taroni

Proceedings Volume 11639, 116390M (2021) https://doi.org/10.1117/12.2578858

KEYWORDS: Lung, Diffuse optical imaging, Signal detection, Optical properties, Monte Carlo methods, Chest, Silicon photomultipliers, Sensors, Pulsed laser operation, Physiology

Read Abstract +

Proceedings Article | 5 March 2021 Presentation

Presentation

Optimization of diffuse correlation spectroscopy instrumental and experimental parameters based on precision targets

Lorenzo Cortese, Giuseppe Lo Presti, Marco Pagliazzi, Jonas Fischer, Martina Giovannella, Marta Zanoletti, Fabio Ferri, Fabrizio Martelli, Alberto Dalla Mora, Davide Contini, Stanislaw Wojtkiewicz, Hamid Dehghani, Udo Weigel, Turgut Durduran

Proceedings Volume 11639, 116390X (2021) https://doi.org/10.1117/12.2578237

KEYWORDS: Spectroscopes, Tissue optics, Temporal resolution, Blood circulation, Speckle, Sensors, Physiology, Photon counting, Near infrared spectroscopy, Light scattering

Read Abstract +

Proceedings Article | 5 March 2021 Presentation + Paper

Presentation + Paper

“Walking” into freely moving brain monitoring via real-time TD-NIRS

Michele Lacerenza, Mauro Buttafava, Lorenzo Spinelli, Alberto Tosi, Alberto Dalla Mora, Antonio Pifferi, Bruno Cozzi, Alessandro Torricelli, Franco Zappa, Davide Contini

Proceedings Volume 11639, 116390V (2021) https://doi.org/10.1117/12.2578196

KEYWORDS: Brain, Oximetry, Pathology, Tissue optics, Tissues, Standards development, Semiconductor lasers, Oximeters, Near infrared spectroscopy, Medicine

Read Abstract +

Proceedings Article | 5 March 2021 Presentation

Presentation

Preliminary clinical study of the potential of multi-modal optical/ultrasound LUCA platform for improved thyroid cancer screening

Lorenzo Cortese, Giuseppe Lo Presti, Pablo Fernandez Esteberena, Marta Zanoletti, Mauro Buttafava, Marco Renna, Davide Contini, Alberto Dalla Mora, Antonio Pifferi, Paola Taroni, Alberto Tosi, Gloria Aranda, Sabina Ruiz Janer, Mattia Squarcia, Felicia Hanzu, Mireia Mora Porta, Stanislaw Wojtkiewicz, Hamid Dehghani, Udo Weigel, Sixte de Fraguier, An Nguyen-Dinh, Bogdan Rosinski, Turgut Durduran

Proceedings Volume 11639, 116390L (2021) https://doi.org/10.1117/12.2577248

Read Abstract +

Proceedings Article | 5 March 2021 Presentation + Paper

Presentation + Paper

A multi-laboratory comparison of photon migration instruments and their performances: the BitMap exercise

Sri Rama Pranav Kumar Lanka, Lin Yang, David Orive-Miguel, Joshua Deepak Veesa, Susanna Tagliabue, Aleh Sudakou, Saeed Samaei, Mario Forcione, Zuzana Kovacsova, Anurag Behera, Thomas Gladytz, Dirk Grosenick, Lionel Hervé, Giuseppe Lo Presti, Lorenzo Cortese, Turgut Durduran, Karolina Bejm, Magdalena Morawiec, Piotr Sawosz, Michal Kacprzak, Anna Gerega, Adam Liebert, Antonio Belli, Ilias Tachtsidis, Frédéric Lange, Gemma Bale, Luca Baratelli, Sylvain Gioux, Alexander Kalyanov, Martin Wolf, Sanathana Konugolu Venkata Sekar, Marta Zanoletti, Ileana Pirovano, Michele Lacerenza, Lina Qiu, Edoardo Ferocino, Giulia Maffeis, Caterina Amendola, Lorenzo Colombo, Mauro Buttafava, Marco Renna, Laura Di Sieno, Rebecca Re, Andrea Farina, Lorenzo Spinelli, Alberto Dalla Mora, Davide Contini, Alessandro Torricelli, Alberto Tosi, Paola Taroni, Hamid Dehghani, Heidrun Wabnitz, Antonio Pifferi

Proceedings Volume 11639, 116390F (2021) https://doi.org/10.1117/12.2578521

KEYWORDS: Raster graphics, Photonic devices, Tissue optics, Spectroscopes, Oximetry, Optical components, Mammography, Imaging spectroscopy, Functional imaging

Read Abstract +

Proceedings Article | 5 March 2021 Presentation + Paper

Presentation + Paper

SOLUS: an innovative multimodal imaging system to improve breast cancer diagnosis through diffuse optics and ultrasounds

Antonio Pifferi, Alberto Dalla Mora, Laura Di Sieno, Edoardo Ferocino, Alberto Tosi, Enrico Conca, Vincenzo Sesta, Andrea Giudice, Alessandro Ruggeri, Simone Tisa, Alexander Flocke, Bogdan Rosinski, Jean-Marc Dinten, Mathieu Perriollat, Christophe Fraschini, Hélène Sportouche, Simon Arridge, Giuseppe Di Sciacca, Andrea Farina, Pietro Panizza, Elena Venturini, Peter Gordebeke, Pamela Zolda, Paola Taroni

Proceedings Volume 11639, 116390C (2021) https://doi.org/10.1117/12.2576778

KEYWORDS: Ultrasonography, Multimodal imaging, Imaging systems, Diffuse optical imaging, Breast cancer, Tissue optics, Sensors, Picosecond phenomena, Transducers, Tomography

Read Abstract +

SPIE Journal Paper | 22 February 2021 Open Access

Open Access

Monitoring the motor cortex hemodynamic response function in freely moving walking subjects: a time-domain fNIRS pilot study

Michele Lacerenza, Lorenzo Spinelli, Mauro Buttafava, Alberto Dalla Mora, Franco Zappa, Antonio Pifferi, Alberto Tosi, Bruno Cozzi, Alessandro Torricelli, Davide Contini

NPh, Vol. 8, Issue 01, 015006, (February 2021) https://doi.org/10.1117/12.10.1117/1.NPh.8.1.015006

KEYWORDS: Hemodynamics, Brain, Neurophotonics, Near infrared spectroscopy, Tissues, Functional magnetic resonance imaging, Photons, Electroencephalography, Amplifiers, Absorption

Read Abstract +

Proceedings Article | 21 February 2020 Paper

Paper

A wearable time domain near infrared spectroscopy system

M. Lacerenza, M. Buttafava, M. Renna, A. Torricelli, A. Tosi, A. Dalla Mora, F. Zappa, A. Pifferi, D. Contini

Proceedings Volume 11237, 1123702 (2020) https://doi.org/10.1117/12.2544271

KEYWORDS: Brain, Near infrared spectroscopy, Hemodynamics, Optical properties, Tissue optics, Tissues, Motion measurement, Absorption, Scattering, In vivo imaging

Read Abstract +

Proceedings Article | 22 July 2019 Paper

Paper

Solid heterogeneous phantoms for multimodal ultrasound and diffuse optical imaging: an outcome of the SOLUS project for standardization

Laura Di Sieno, Rinaldo Cubeddu, Hélène Sportouche, David Savéry, Sanathana Konugolu Venkata Sekar, Bogdan Rosinski, Andrea Farina, Edoardo Ferocino, Pranav Lanka, Paola Taroni, Antonio Pifferi, Alberto Dalla Mora

Proceedings Volume 11075, 1107516 (2019) https://doi.org/10.1117/12.2526645

KEYWORDS: Ultrasonography, Optical properties, Diffuse optical imaging, Silicon, Imaging systems, Solids, Multimodal imaging, Tissues, Absorption, Calibration

Read Abstract +

SPIE Journal Paper | 12 July 2019 Open Access

Open Access

Effects of the instrument response function and the gate width in time-domain diffuse correlation spectroscopy: model and validations

Lorenzo Colombo, Marco Pagliazzi, Sanathana Konugolu Venkata Sekar, Davide Contini, Alberto Dalla Mora, Lorenzo Spinelli, Alessandro Torricelli, Turgut Durduran, Antonio Pifferi

NPh, Vol. 6, Issue 03, 035001, (July 2019) https://doi.org/10.1117/12.10.1117/1.NPh.6.3.035001

KEYWORDS: Photons, Sensors, Instrument modeling, Scattering, Optical properties, Picosecond phenomena, Diffusion, Spectroscopes, Absorption, Neurophotonics

Read Abstract +

Proceedings Article | 11 July 2019 Paper

Paper

Spectral approach to time domain diffuse optical tomography for breast cancer: validation on meat phantoms

Edoardo Ferocino, Giuseppe Di Sciacca, Laura Di Sieno, Alberto Dalla Mora, Antonio Pifferi, Simon Arridge, Fabrizio Martelli, Paola Taroni, Andrea Farina

Proceedings Volume 11074, 1107408 (2019) https://doi.org/10.1117/12.2526649

KEYWORDS: Breast cancer, Diffuse optical tomography, Tissues, Absorption, Scattering, Breast, Mie scattering, Software development, Chromophores, Tissue optics

Read Abstract +

Proceedings Article | 11 July 2019 Paper

Paper

The BITMAP exercise: a multi-laboratory performance assessment campaign of diffuse optical instrumentation

Pranav Lanka, Lin Yang, David Orive-Miguel, Joshua Deepak Veesa, Susanna Tagliabue, Aleh Sudakou, Saeed Samaei, Mario Forcione, Zuzana Kovacsova, Anurag Behera, Lionel Hervé, Turgut Durduran, Adam Liebert, Piotr Sawosz, Antonio Belli, Ilias Tachtsidis, Alberto Dalla Mora, Hamid Dehghani, Heidrun Wabnitz, Antonio Pifferi

Proceedings Volume 11074, 110741A (2019) https://doi.org/10.1117/12.2527120

KEYWORDS: Optical instrument design, Spectroscopy, Oximeters, Standards development, Biomedical engineering, Diffuse optical imaging, Absorption, Scattering

Read Abstract +

Proceedings Article | 11 July 2019 Paper

Paper

A wearable time domain near-infrared spectroscopy system

M. Lacerenza, M. Buttafava, M. Renna, L. Marchesi, A. Torricelli, A. Tosi, A. Dalla Mora, F. Zappa, A. Pifferi, D. Contini

Proceedings Volume 11074, 1107404 (2019) https://doi.org/10.1117/12.2527057

KEYWORDS: Near infrared spectroscopy, Hemodynamics, Brain, Absorption, Scattering, Single photon detectors, Electronics, Control systems, Solids, In vivo imaging

Read Abstract +

Proceedings Article | 11 July 2019 Paper

Paper

The BitMap dataset: an open dataset on performance assessment of diffuse optics instruments

David Orive-Miguel, Pranav Lanka, Lin Yang, Susanna Tagliabue, Aleh Sudakou, Saeed Samaei, Joshua Deepak Veesa, Mario Forcione, Zuzana Kovacsova, Anurag Behera, Lionel Hervé, Turgut Durduran, Adam Liebert, Piotr Sawosz, Antonio Belli, Ilias Tachtsidis, Alberto Dalla Mora, Jérôme Mars, Laurent Condat, Alessandro Torricelli, Hamid Dehghani, Heidrun Wabnitz, Antonio Pifferi

Proceedings Volume 11074, 110741B (2019) https://doi.org/10.1117/12.2526728

KEYWORDS: Diffuse optical imaging, Spectrometers, Oximeters, Transparency, Standards development, Biomedical engineering

Read Abstract +

Proceedings Article | 11 July 2019 Paper

Paper

Effects of ultrasound impedance matching fluids on diffuse optical measurements

Laura Di Sieno, Davide Contini, Giuseppe Lo Presti, Lorenzo Cortese, Tony Mateo, Bogdan Rosinski, Elena Venturini, Pietro Panizza, Mireia Mora, Gloria Aranda, Mattia Squarcia, Andrea Farina, Turgut Durduran, Paola Taroni, Antonio Pifferi, Alberto Dalla Mora

Proceedings Volume 11074, 110742T (2019) https://doi.org/10.1117/12.2526925

KEYWORDS: Ultrasonography, Scattering, Optical testing, Tissues, Light scattering, Absorption, Fluid dynamics, Interfaces, Tissue optics, Geometrical optics

Read Abstract +

Proceedings Article | 11 July 2019 Paper

Paper

Large area SiPM and high throughput timing electronics: toward new generation time-domain instruments

Anurag Behera, Laura Di Sieno, Sumeet Rohilla, Antonio Pifferi, Alessandro Torricelli, Davide Contini, Benedikt Krämer, Felix Koberling, Alberto Dalla Mora

Proceedings Volume 11074, 1107402 (2019) https://doi.org/10.1117/12.2526792

KEYWORDS: Electronics, Sensors, Absorption, Optical properties, Scattering, Tissue optics, Picosecond phenomena, In vivo imaging, Brain activation, Signal detection

Read Abstract +

Proceedings Article | 11 July 2019 Paper

Paper

In vivo time domain speckle contrast optical spectroscopy

M. Pagliazzi, E. Vidal-Rosas, S. Konugolu Venkata Sekar, L. Di Sieno, L. Colombo, D. Contini, A. Torricelli, A. Pifferi, A. Dalla Mora, J. Culver, T. Durduran

Proceedings Volume 11074, 1107411 (2019) https://doi.org/10.1117/12.2526651

KEYWORDS: Speckle, Sensors, Photons, Optical spectroscopy, Blood circulation, Tissue optics, Electronics, In vivo imaging, Tissues, Reflectivity

Read Abstract +

Proceedings Article | 11 July 2019 Paper

Paper

In vivo time-domain diffuse correlation spectroscopy of the human muscle above 1000 nm

L. Colombo, M. Pagliazzi, S. Konugolu Venkata Sekar, D. Contini, A. Dalla Mora, L. Spinelli, A. Torricelli, T. Durduran, A. Pifferi

Proceedings Volume 11074, 110742V (2019) https://doi.org/10.1117/12.2527065

KEYWORDS: In vivo imaging, Signal to noise ratio, Spectroscopy, Blood circulation, Laser sources, Absorption, Tissue optics, Scattering, Indium gallium arsenide, Photomultipliers

Read Abstract +

Proceedings Article | 11 July 2019 Paper

Paper

Time-Resolved multi-wavelength, dual-channel system for diffuse optical spectroscopy: performance assessment

Marta Zanoletti, Marco Renna, Mauro Buttafava, Anurag Behera, Pranav Lanka, Laura Di Sieno, Alberto Dalla Mora, Alberto Tosi, Davide Contini

Proceedings Volume 11074, 110742Q (2019) https://doi.org/10.1117/12.2527049

KEYWORDS: Absorption, Time resolved spectroscopy, Scattering, Tissues, Spectroscopy, Solids, Photons, Blood, Picosecond phenomena, Signal processing

Read Abstract +

Proceedings Article | 11 July 2019 Paper

Paper

Pilot measurement of the microvascular blood flow of thyroid nodules by diffuse optics

G. Lo Presti, G. Aranda, D. Contini, L. Cortese, A. Dalla Mora, S. de Fraguier, R. Gomis, F. Hanzu, M. Mora, A. Pifferi, B. Rosinski, S. Konugolu Venkata Sekar, M. Squarcia, P. Taroni, UM Weigel, T. Durduran

Proceedings Volume 11074, 110741L (2019) https://doi.org/10.1117/12.2527548

KEYWORDS: Blood circulation, Diffuse optical imaging, Ultrasonography, Surgery, Tissue optics, Cancer, Scattering, Optical properties, Blood, Data acquisition

Read Abstract +

Proceedings Article | 11 July 2019 Paper

Paper

The LUCA device: laser and ultrasound co-analyzer for thyroid nodules

L. Cortese, G. Aranda, M. Buttafava, D. Contini, A. Dalla Mora, S. de Fraguier, H. Dehghani, E. García, R. Gomis, F. Hanzu, F. Josè Torra, K. Krischak, G. Lo Presti, M. Mora, A. Pifferi, M. Renna, B. Rosinski, S. Konugolu Venkata Sekar, M. Squarcia, P. Taroni, A. Tosi, U. Weigel, S. Wojtkiewicz, M. Zanoletti, P. Zolda, T. Durduran

Proceedings Volume 11074, 1107410 (2019) https://doi.org/10.1117/12.2526607

KEYWORDS: Ultrasonography, Biomedical optics, Cancer, Time resolved spectroscopy, Scattering, Data acquisition, Blood circulation, Standards development, Sensors, Diffusion

Read Abstract +

Proceedings Article | 14 May 2019 Presentation

Presentation

Time-resolved imaging system based on adaptive structured light illumination and single-pixel camera detection (Conference Presentation)

Cosimo D'Andrea, Andrea Farina, Alessia Candeo, Marta Betcke, Alberto Dalla Mora, Rudi Lussana, Federica Villa, Andrea Bassi, Gianluca Valentini, Simon Arridge

Proceedings Volume 10978, 1097804 (2019) https://doi.org/10.1117/12.2518639

KEYWORDS: Imaging systems, Cameras, Structured light, Biomedical optics, Fluorescence lifetime imaging, LIDAR, Sensors, Optical tomography, Tumors, Brain activation

Read Abstract +

Proceedings Article | 4 March 2019 Presentation

Presentation

Novel time-resolved detector for fluorescence lifetime imaging (Conference Presentation)

Cosimo D'Andrea, Andrea Farina, Alessia Candeo, Alberto Dalla Mora, Rudi Lussana, Federica Villa, Gianluca Valentini, Simon Arridge

Proceedings Volume 10883, 108830P (2019) https://doi.org/10.1117/12.2510214

KEYWORDS: Fluorescence lifetime imaging, Sensors, Cameras, Imaging systems, Image sensors, Biomedical optics, Tissue optics, Compressed sensing, Microscopy, Associative arrays

Read Abstract +

Proceedings Article | 1 March 2019 Presentation + Paper

Presentation + Paper

Multi-wavelength time domain diffuse optical tomography for breast cancer: initial results on silicone phantoms

Edoardo Ferocino, Giuseppe Di Sciacca, Laura Di Sieno, Alberto Dalla Mora, Antonio Pifferi, Simon Arridge, Fabrizio Martelli, Paola Taroni, Andrea Farina

Proceedings Volume 10874, 108741N (2019) https://doi.org/10.1117/12.2508657

KEYWORDS: Absorption, Silicon, Scattering, Breast cancer, Optical properties, Diffuse optical tomography, Tissue optics, Breast, Sensors, Tissues

Read Abstract +

Proceedings Article | 1 March 2019 Presentation + Paper

Presentation + Paper

Bioresorbable fibers for time-domain diffuse optical measurements: a step toward next generation optical implantable devices

Laura Di Sieno, Nadia Boetti, Alberto Dalla Mora, Diego Pugliese, Andrea Farina, Sanathana Konugolu Venkata Sekar, Edoardo Ceci-Ginistrelli, Davide Janner, Antonio Pifferi, Daniel Milanese

Proceedings Volume 10874, 1087409 (2019) https://doi.org/10.1117/12.2509501

KEYWORDS: Optical fibers, Photons, Scattering, Absorption, Sensors, Tissues, Breast, Optical testing, Signal attenuation, Optical properties

Read Abstract +

Proceedings Article | 1 March 2019 Presentation + Paper

Presentation + Paper

Multi-wavelength dual-detection channel system for time-resolved near-infrared spectroscopy

Marco Renna, Mauro Buttafava, Anurag Behera, Marta Zanoletti, Laura Di Sieno, Alberto Dalla Mora, Davide Contini, Alberto Tosi

Proceedings Volume 10874, 1087408 (2019) https://doi.org/10.1117/12.2509706

KEYWORDS: Picosecond phenomena, Semiconductor lasers, Laser sources, Near infrared spectroscopy, Sensors, Optical fibers, Scattering, Field programmable gate arrays, Absorption, Pulsed laser operation

Read Abstract +

Proceedings Article | 17 May 2018 Presentation + Paper

Presentation + Paper

Study of optimal measurement conditions for time-domain diffuse optics systems

Anurag Behera, Laura Di Sieno, Antonio Pifferi, Fabrizio Martelli, Alberto Dalla Mora

Proceedings Volume 10685, 1068514 (2018) https://doi.org/10.1117/12.2307370

KEYWORDS: Photons, Absorption, Diffusion, Diffuse optical imaging, Scattering, Laser scattering, Geometrical optics, Picosecond phenomena, Sensors, Optical properties

Read Abstract +

Light is a powerful non-invasive tool that can be exploited to probe highly scattering media like biological tissues for different purposes, from the detection of brain activity to the characterization of cancer lesions. In the last decade, timedomain diffuse optics (TDDO) systems demonstrated improved sensitivity when using time-gated acquisition chains and short source-detector separations (ρ), both theoretically and experimentally. However, the sensitivity to localized absorption changes buried inside a diffusive medium strongly depends on many parameters such as: SDS, laser power, delay and width of the gating window, absorption and scattering properties of the medium, instrument response function (IRF) shape, etc. In particular, relevant effects due to slow tails in the IRF were noticed, with detrimental effects on performances. We present simulated experimental results based on the diffusion approximation of the Radiative Transfer Equation and the perturbation theory subjected to the Born approximation. To quantify the system sensitivity to deep (few cm) and localized absorption perturbations, we exploited contrast and contrast-to-noise ratio (CNR), which are internationally agreed on standardized figures of merit. The purpose of this study is to determine which parameters have the greatest impact on these figures of merit, thus also providing a range of best operative conditions. The study is composed by two main stages: the former is a comparison between simulations and measurements on tissue-mimicking phantom, while the latter is a broad simulation study in which all relevant parameters are tuned to determine optimal measurement conditions. This study essentially demonstrates that under the influence of the slow tails in the IRF, the use of a small SDS no longer corresponds to optimal contrast and CNR. This work sets the ground for future studies with next-generation of TDDO components, presently under development, providing useful hints on relevant features to which one should take care when designing TDDO components.

SPIE Journal Paper | 19 August 2017 Open Access

Open Access

Miniaturized pulsed laser source for time-domain diffuse optics routes to wearable devices

Laura Di Sieno, Jan Nissinen, Lauri Hallman, Edoardo Martinenghi, Davide Contini, Antonio Pifferi, Juha Kostamovaara, Alberto Mora

JBO, Vol. 22, Issue 08, 085004, (August 2017) https://doi.org/10.1117/12.10.1117/1.JBO.22.8.085004

KEYWORDS: Diffuse optical imaging, Pulsed laser operation, Sensors, Laser sources, Picosecond phenomena, Absorption, Semiconductor lasers, Tissue optics, Optical properties, Scattering

Read Abstract +

Proceedings Article | 28 July 2017 Paper

Paper

Thyroid tissue constituents characterization and application to in vivo studies by broadband (600-1200 nm) diffuse optical spectroscopy

Sanathana Konugolu Venkata Sekar, Andrea Farina, Alberto dalla Mora, Paola Taroni, Claus Lindner, Mireia Mora, Parisa Farzam, Marco Pagliazzi, Mattia Squarcia, Irene Halperin, Felicia Hanzu, Hamid Dehghani, Turgut Durduran, Antonio Pifferi

Proceedings Volume 10411, 1041107 (2017) https://doi.org/10.1117/12.2287179

Read Abstract +

Proceedings Article | 28 July 2017 Paper

Paper

Performance evaluation of time-domain multispectral diffuse optical tomography in the reflection geometry

Judy Zouaoui, Laura Di Sieno, David Orive-Miguel, Lionel Hervé, Antonio Pifferi, Andrea Farina, Alberto Dalla Mora, Jacques Derouard, Jérôme Mars, Laurent Condat, Jean-Marc Dinten

Proceedings Volume 10412, 1041208 (2017) https://doi.org/10.1117/12.2285811

KEYWORDS: Diffuse optical tomography, Tomography, Image restoration, Photon counting, Photodetectors

Read Abstract +

Proceedings Article | 28 July 2017 Paper

Paper

Attractive new technologies for 7-wavelength time domain optical mammography

Edoardo Ferocino, Edoardo Martinenghi, Alberto Dalla Mora, Antonio Pifferi, Rinaldo Cubeddu, Paola Taroni

Proceedings Volume 10412, 1041202 (2017) https://doi.org/10.1117/12.2286058

Read Abstract +

Proceedings Article | 28 July 2017 Paper

Paper

Non-contact time-domain imaging of functional brain activation and heterogeneity of superficial signals

H. Wabnitz, M. Mazurenka, L. Di Sieno, D. Contini, A. Dalla Mora, A. Farina, Y. Hoshi, E. Kirilina, R. Macdonald, A. Pifferi

Proceedings Volume 10412, 104120J (2017) https://doi.org/10.1117/12.2286077

KEYWORDS: Brain activation, Biomedical optics

Read Abstract +

Proceedings Article | 28 July 2017 Paper

Paper

Time-domain diffuse optics using bioresorbable fibers: a proof-of-principle study

Laura Di Sieno, Nadia Boetti, Alberto Dalla Mora, Diego Pugliese, Andrea Farina, Sanathana Konugolu Venkata Sekar, Edoardo Ceci-Ginistrelli, Davide Janner, Antonio Pifferi, Daniel Milanese

Proceedings Volume 10413, 104130E (2017) https://doi.org/10.1117/12.2290147

Read Abstract +

SPIE Journal Paper | 31 January 2017 Open Access

Open Access

Diffuse optical characterization of collagen absorption from 500 to 1700 nm

Sanathana Konugolu Venkata Sekar, Ilaria Bargigia, Alberto Dalla Mora, Paola Taroni, Alessandro Ruggeri, Alberto Tosi, Antonio Pifferi, Andrea Farina

JBO, Vol. 22, Issue 01, 015006, (January 2017) https://doi.org/10.1117/12.10.1117/1.JBO.22.1.015006

KEYWORDS: Absorption, Collagen, Scattering, Tissue optics, In vivo imaging, Bone, Tissues, Short wave infrared radiation, Biomedical optics, Luminescence

Read Abstract +

SPIE Journal Paper | 12 October 2016 Open Access

Open Access

Probe-hosted silicon photomultipliers for time-domain functional near-infrared spectroscopy: phantom and in vivo tests

Rebecca Re, Edoardo Martinenghi, Alberto Dalla Mora, Davide Contini, Antonio Pifferi, Alessandro Torricelli

NPh, Vol. 3, Issue 04, 045004, (October 2016) https://doi.org/10.1117/12.10.1117/1.NPh.3.4.045004

KEYWORDS: Sensors, Optical fibers, Silicon photomultipliers, In vivo imaging, Absorption, Hemodynamics, Brain, Near infrared spectroscopy, Signal detection, Electroencephalography

Read Abstract +

SPIE Journal Paper | 17 June 2016 Open Access

Open Access

New frontiers in time-domain diffuse optics, a review

Antonio Pifferi, Davide Contini, Alberto Dalla Mora, Andrea Farina, Lorenzo Spinelli, Alessandro Torricelli

JBO, Vol. 21, Issue 09, 091310, (June 2016) https://doi.org/10.1117/12.10.1117/1.JBO.21.9.091310

KEYWORDS: Diffuse optical imaging, Sensors, Tissues, Near infrared spectroscopy, Optical fibers, Absorption, Electronics, Picosecond phenomena, Imaging systems, Continuous wave operation

Read Abstract +

SPIE Journal Paper | 2 February 2016 Open Access

Open Access

Toward noninvasive assessment of flap viability with time-resolved diffuse optical tomography: a preclinical test on rats

Georges Bettega, Laura Di Sieno, Marion Aribert, Michel Berger, Cynthia Hamou, Alberto Dalla Mora, Agathe Puszka, Henri Grateau, Davide Contini, Lionel Hervé, Jean-Luc Coll, Jean-Marc Dinten, Antonio Pifferi, Anne Planat-Chrétien

JBO, Vol. 21, Issue 02, 025004, (February 2016) https://doi.org/10.1117/12.10.1117/1.JBO.21.2.025004

KEYWORDS: Surgery, Diffuse optical tomography, Veins, Optical fibers, Tomography, Tissues, Skin, Blood, Doppler tomography, 3D acquisition

Read Abstract +

Proceedings Article | 16 July 2015 Paper

Paper

Time-resolved diffuse optical tomography for non-invasive flap viability assessment: pre-clinical tests on rats

L. Di Sieno, G. Bettega, M. Berger, C. Hamou, M. Aribert, A. Dalla Mora, A. Puszka, H. Grateau, D. Contini, L. Hervé, J.-L. Coll, J.-M. Dinten, A. Pifferi, A. Planat-Chrétien

Proceedings Volume 9538, 95380N (2015) https://doi.org/10.1117/12.2183425

KEYWORDS: Tissues, Veins, Photons, Diffuse optical tomography, Surgery, Neodymium, Arteries, Optical fibers, Sensors, Spatial resolution

Read Abstract +

Proceedings Article | 16 July 2015 Paper

Paper

Time-domain diffuse optics: towards next generation devices

Davide Contini, Alberto Dalla Mora, Simon Arridge, Fabrizio Martelli, Alberto Tosi, Gianluca Boso, Andrea Farina, Turgut Durduran, Edoardo Martinenghi, Alessandro Torricelli, Antonio Pifferi

Proceedings Volume 9538, 95380A (2015) https://doi.org/10.1117/12.2183693

KEYWORDS: Sensors, Diffuse optical imaging, Vertical cavity surface emitting lasers, Absorption, Brain, Information technology, Standards development, Light scattering, Scattering

Read Abstract +

Proceedings Article | 16 July 2015 Paper

Paper

In-depth quantification by using multispectral time-resolved diffuse optical tomography

Judy Zouaoui, Lionel Hervé, Laura Di Sieno, Anne Planat-Chrétien, Michel Berger, Alberto Dalla Mora, Antonio Pifferi, Jacques Derouard, Jean-Marc Dinten

Proceedings Volume 9538, 95380C (2015) https://doi.org/10.1117/12.2183819

KEYWORDS: Chromophores, Diffuse optical tomography, Absorption, Photons, Optical fibers, Tissues, Sensors, Transform theory, Light, Liquids

Read Abstract +

Proceedings Article | 16 July 2015 Paper

Paper

Broadband time-resolved diffuse optical spectrometer for clinical diagnostics: characterization and in-vivo measurements in the 600-1350 nm spectral range

Sanathana Konugolu Venkata Sekar, Andrea Farina, Edoardo Martinenghi, Alberto Dalla Mora, Paola Taroni, Antonio Pifferi, Turgut Durduran, Marco Pagliazzi, Claus Lindner, Parisa Farzam, Mireia Mora, Mattia Squarcia, A. Urbano-Ispizua

Proceedings Volume 9538, 95380R (2015) https://doi.org/10.1117/12.2183835

KEYWORDS: In vivo imaging, Tissues, Absorption, Sensors, Scattering, Spectroscopy, Diagnostics, Collagen, Laser scattering, Tissue optics

Read Abstract +

Proceedings Article | 16 July 2015 Paper

Paper

Time-resolved diffused optical characterization of key tissue constituents of human bony prominence locations

Sanathana Konugolu Venkata Sekar, Andrea Farina, Edoardo Martinenghi, Alberto Dalla Mora, Paola Taroni, Antonio Pifferi, Eugènia Negredo, Jordi Puig, Roser Escrig, Quim Rosales, Claus Lindner, Marco Pagliazzi, Turgut Durduran

Proceedings Volume 9538, 95380X (2015) https://doi.org/10.1117/12.2183724

KEYWORDS: Bone, Tissue optics, Absorption, Scattering, Tissues, Collagen, Dual energy x-ray absorptiometry, Sensors, Pathology, Light scattering

Read Abstract +

Proceedings Article | 16 July 2015 Paper

Paper

Non-contact scanning time-domain functional optical imaging of the adult human brain

Heidrun Wabnitz, Mikhail Mazurenka, Katja Fuchs, Laura Di Sieno, Gianluca Boso, Davide Contini, Alberto Dalla Mora, Alberto Tosi, Yoko Hoshi, Antonio Pifferi, Rainer Macdonald

Proceedings Volume 9538, 953802 (2015) https://doi.org/10.1117/12.2183288

KEYWORDS: Photons, Tissue optics, Sensors, Tissues, Absorption, Scanners, Brain activation, Brain, Signal detection, Spatial resolution

Read Abstract +

Proceedings Article | 18 March 2015 Paper

Paper

Diffuse optical tomography by using time-resolved single pixel camera

A. Farina, M. Lepore, L. Di Sieno, Alberto Dalla Mora, N. Ducros, A. Pifferi, G. Valentini, Simon Arridge, C. D'Andrea

Proceedings Volume 9319, 93191K (2015) https://doi.org/10.1117/12.2079650

KEYWORDS: Cameras, Diffuse optical tomography, Digital micromirror devices, Luminescence, Data acquisition, Charge-coupled devices, Optical tomography, Scattering, Sensors, Structured light

Read Abstract +

Proceedings Article | 5 March 2015 Paper

Paper

Towards next generation time-domain diffuse optics devices

Alberto Dalla Mora, Davide Contini, Simon Arridge, Fabrizio Martelli, Alberto Tosi, Gianluca Boso, Andrea Farina, Turgut Durduran, Edoardo Martinenghi, Alessandro Torricelli, Antonio Pifferi

Proceedings Volume 9319, 93191J (2015) https://doi.org/10.1117/12.2078955

KEYWORDS: Sensors, Photons, Diffuse optical imaging, Absorption, Vertical cavity surface emitting lasers, Electronics, Single photon detectors, Pulse generators, Brain

Read Abstract +

Proceedings Article | 8 February 2015 Paper

Paper

High linearity SPAD and TDC array for TCSPC and 3D ranging applications

Federica Villa, Rudi Lussana, Danilo Bronzi, Alberto Dalla Mora, Davide Contini, Simone Tisa, Alberto Tosi, Franco Zappa

Proceedings Volume 9370, 93701U (2015) https://doi.org/10.1117/12.2077847

KEYWORDS: Picosecond phenomena, Photodetectors, Time correlated photon counting, 3D metrology, Electronics, Clocks, Ranging, CMOS technology, 3D applications, Photon counting

Read Abstract +

Proceedings Article | 4 March 2014 Paper

Paper

Multi-wavelength and time-domain diffuse optical tomography data processing by using a material basis and Mellin-Laplace transform

Lionel Hervé, Anne Planat-Chrétien, Laura Di Sieno, Michel Berger, Agathe Puszka, Alberto Dalla Mora, Davide Contini, Gianluca Boso, Jean-Marc Dinten

Proceedings Volume 8952, 89520D (2014) https://doi.org/10.1117/12.2039506

KEYWORDS: Absorption, Photons, Sensors, Optical tomography, Oxygen, Chromophores, 3D modeling, Tissues, Data processing, Picosecond phenomena

Read Abstract +

Proceedings Article | 17 February 2014 Paper

Paper

Optimal arrangements of fiber optic probes to enhance the spatial resolution in depth for 3D reflectance diffuse optical tomography with time-resolved measurements performed with fast-gated single-photon avalanche diodes

Agathe Puszka, Laura Di Sieno, Alberto Dalla Mora, Antonio Pifferi, Davide Contini, Gianluca Boso, Alberto Tosi, Lionel Hervé, Anne Planat-Chrétien, Anne Koenig, Jean-Marc Dinten

Proceedings Volume 8937, 89370Z (2014) https://doi.org/10.1117/12.2036351

KEYWORDS: Spatial resolution, Sensors, Fiber optics, Diffuse optical tomography, Avalanche photodiodes, 3D metrology, Reflectivity, Photons, Fiber optics tests, Liquids

Read Abstract +

Proceedings Article | 24 June 2013 Paper

Paper

Functional near-infrared spectroscopy at small source-detector distance by means of high dynamic-range fast-gated SPAD acquisitions: first in-vivo measurements

L. Di Sieno, D. Contini, A. Dalla Mora, A. Torricelli, L. Spinelli, R. Cubeddu, A. Tosi, G. Boso, A. Pifferi

Proceedings Volume 8804, 880402 (2013) https://doi.org/10.1117/12.2032492

KEYWORDS: Photons, Optical fibers, Near infrared spectroscopy, Sensors, Signal to noise ratio, In vivo imaging, Picosecond phenomena, Tissue optics, Avalanche photodiodes, Biomedical optics

Read Abstract +

Proceedings Article | 14 June 2013 Paper

Paper

In-vivo optical spectroscopy in the time-domain beyond 1100 nm

I. Bargigia, A. Tosi, A. Bahgat Shehata, A. Della Frera, A. Farina, A. Bassi, P. Taroni, A. Dalla Mora, F. Zappa, R. Cubeddu, A. Pifferi

Proceedings Volume 8799, 879902 (2013) https://doi.org/10.1117/12.2032521

KEYWORDS: Absorption, In vivo imaging, Breast, Scattering, Optical spectroscopy, Tissues, Sensors, Monte Carlo methods, Collagen, Biomedical optics

Read Abstract +

Proceedings Article | 14 June 2013 Paper

Paper

A non-contact time-domain scanning brain imaging system: first in-vivo results

M. Mazurenka, L. Di Sieno, G. Boso, D. Contini, A. Pifferi, A. Dalla Mora, A. Tosi, H. Wabnitz, R. Macdonald

Proceedings Volume 8799, 87990L (2013) https://doi.org/10.1117/12.2032386

KEYWORDS: Photons, Tissues, In vivo imaging, Tissue optics, Brain, Imaging systems, Near infrared spectroscopy, Skin, Neodymium, Biomedical optics

Read Abstract +

Proceedings Article | 14 June 2013 Paper

Paper

Experimental results on time-resolved reflectance diffuse optical tomography with fast-gated SPADs

Agathe Puszka, Laura Di Sieno, Alberto Dalla Mora, Antonio Pifferi, Davide Contini, Gianluca Boso, Alberto Tosi, Anne Planat-Chrétien, Lionel Hervé, Anne Koenig, Jean-Marc Dinten

Proceedings Volume 8799, 879903 (2013) https://doi.org/10.1117/12.2033275

KEYWORDS: Reflectivity, Sensors, Diffuse optical tomography, Reconstruction algorithms, Detection and tracking algorithms, Avalanche photodiodes, Tissue optics, Biomedical optics, Image restoration, Photon counting

Read Abstract +

Proceedings Article | 14 March 2013 Paper

Paper

Memory effect in gated single-photon avalanche diodes: a limiting noise contribution similar to afterpulsing

D. Contini, A. Dalla Mora, L. Di Sieno, R. Cubeddu, A. Tosi, G. Boso, A. Pifferi

Proceedings Volume 8619, 86191L (2013) https://doi.org/10.1117/12.2005013

KEYWORDS: Sensors, Photons, Avalanche photodiodes, Pulsed laser operation, Silicon, Optical testing, Solids, Spectroscopy, Signal detection, Picosecond phenomena

Read Abstract +

Proceedings Article | 21 January 2012 Paper

Paper

Fast-gated single-photon detection module with 200 ps transitions running up to 50 MHz with 30 ps resolution

G. Boso, A. Dalla Mora, A. Tosi, A. Della Frera, F. Zappa

Proceedings Volume 8268, 82681U (2012) https://doi.org/10.1117/12.908584

KEYWORDS: Picosecond phenomena, Sensors, Signal detection, Electronics, Power supplies, Microcontrollers, Pulsed laser operation, Single photon detectors, Silicon, Avalanche photodiodes

Read Abstract +

Proceedings Article | 15 June 2011 Paper

Paper

Time-resolved diffuse optical spectroscopy up to 1700 nm using a time-gated InGaAs/InP single-photon avalanche diode

I. Bargigia, A. Tosi, A. Bahgat Shehata, A. Della Frera, A. Farina, A. Bassi, P. Taroni, A. Dalla Mora, F. Zappa, A. Pifferi

Proceedings Volume 8090, 80900U (2011) https://doi.org/10.1117/12.889775

KEYWORDS: Collagen, Absorption, Avalanche photodiodes, Diffuse optical spectroscopy, Breast, Scattering, Tissues, Biomedical optics, Laser scattering, Spectroscopy

Read Abstract +

Proceedings Article | 15 June 2011 Paper

Paper

Non-contact time-domain scanning brain imager: results of proof of principle tests

M. Mazurenka, A. Jelzow, B. Ebert, H. Wabnitz, D. Contini, L. Spinelli, A. Pifferi, A. Dalla Mora, A. Tosi, R. Macdonald

Proceedings Volume 8088, 80880A (2011) https://doi.org/10.1117/12.889708

KEYWORDS: Photons, Picosecond phenomena, Sensors, Imaging systems, Cameras, Neuroimaging, Brain, Liquids, Near infrared spectroscopy, Confocal microscopy

Read Abstract +

Proceedings Article | 23 February 2011 Paper

Paper

Experimental characterization of afterpulsing and timing jitter of InGaAs/InP SPAD

F. Acerbi, A. Tosi, A. Dalla Mora, M. Anti, F. Zappa

Proceedings Volume 7934, 79340L (2011) https://doi.org/10.1117/12.874811

KEYWORDS: Absorption, Avalanche photodiodes, Sensors, Single photon detectors, Photon counting, Single photon, Picosecond phenomena, Avalanche photodetectors, Quenching (fluorescence), Pulsed laser operation

Read Abstract +

Proceedings Article | 17 February 2011 Paper

Paper

Time-domain diffuse optical spectroscopy up to 1700 nm using an InGaAs/InP single-photon avalanche diode

Ilaria Bargigia, Alberto Tosi, Andrea Farina, Andrea Bassi, Paola Taroni, Andrea Bahgat Shehata, Adriano Della Frera, Alberto Dalla Mora, Franco Zappa, Rinaldo Cubeddu, Antonio Pifferi

Proceedings Volume 7895, 78950C (2011) https://doi.org/10.1117/12.874947

KEYWORDS: Absorption, Collagen, Diffuse optical spectroscopy, Avalanche photodiodes, Scattering, Tissues, Laser scattering, Spectral resolution, Temporal resolution, Picosecond phenomena

Read Abstract +

Proceedings Article | 24 January 2011 Paper

Paper

Advanced single photon counting instrumentation for SPADs

A. Tosi, A. Dalla Mora, A. Della Frera, F. Acerbi, A. Bahgat Shehata, F. Zappa

Proceedings Volume 7945, 79452O (2011) https://doi.org/10.1117/12.875133

KEYWORDS: Picosecond phenomena, Pulse generators, Sensors, Ultrafast phenomena, Avalanche photodiodes, Photon counting, Photodetectors, Single photon, Time correlated photon counting, Reflectance spectroscopy

Read Abstract +

Proceedings Article | 24 January 2011 Paper

Paper

Compact detection module based on InGaAs/InP SPADs for near-infrared single-photon counting up to 1.7 μm

A. Tosi, A. Bahgat Shehata, A. Della Frera, A. Dalla Mora, S. Tisa, F. Acerbi, F. Zappa

Proceedings Volume 7945, 79452L (2011) https://doi.org/10.1117/12.875086

KEYWORDS: Sensors, Single photon detectors, Electronics, Pulse generators, Quantum key distribution, Picosecond phenomena, Signal detection, Photodetectors, Head, Single photon

Read Abstract +

Proceedings Article | 29 April 2010 Paper

Paper

Functional diffuse reflectance spectroscopy at small source-detector distances based on fast-gated single-photon avalanche diodes

Davide Contini, Antonio Pifferi, Lorenzo Spinelli, Alessandro Torricelli, Rinaldo Cubeddu, Fabrizio Martelli, Giovanni Zaccanti, Alberto Dalla Mora, Alberto Tosi, Franco Zappa, Sergio Cova

Proceedings Volume 7681, 768102 (2010) https://doi.org/10.1117/12.852557

KEYWORDS: Diffuse reflectance spectroscopy, Picosecond phenomena, Avalanche photodiodes, Biomedical optics, Photodetectors, Brain, Spatial resolution, Reflectivity, Absorption, Sensors

Read Abstract +

Proceedings Article | 28 April 2010 Paper

Paper

InGaAs/InP SPADs for near-infrared applications: device operating conditions and dedicated electronics

Alberto Tosi, Alberto Dalla Mora, Simone Tisa, Fabio Acerbi, Franco Zappa, Sergio Cova

Proceedings Volume 7681, 76810R (2010) https://doi.org/10.1117/12.850696

KEYWORDS: Sensors, Electronics, Single photon detectors, Avalanche photodiodes, Photodetectors, Single photon, Remote sensing, Resistance, Quenching (fluorescence), Quantum key distribution

Read Abstract +

Proceedings Article | 24 February 2010 Paper

Paper

Fast-gated single-photon detectors boost dynamic range in NIR spectroscopy

A. Tosi, A. Dalla Mora, F. Zappa, S. Cova, D. Contini, A. Pifferi, L. Spinelli, A. Torricelli, R. Cubeddu

Proceedings Volume 7556, 75560G (2010) https://doi.org/10.1117/12.840910

KEYWORDS: Photodetectors, Picosecond phenomena, Sensors, Signal detection, Near infrared spectroscopy, Near infrared, Silicon, Single photon detectors, Time metrology, Biomedical optics

Read Abstract +

Proceedings Article | 23 January 2010 Paper

Paper

Single-photon avalanche diode arrays and CMOS microelectronics for counting, timing, and imaging quantum events

F. Zappa, A. Tosi, A. Dalla Mora, F. Guerrieri, S. Tisa

Proceedings Volume 7608, 76082C (2010) https://doi.org/10.1117/12.840362

KEYWORDS: Sensors, Electronics, Quenching (fluorescence), Photon counting, Avalanche photodiodes, Microelectronics, Photodetectors, Single photon, Single photon detectors, Time correlated photon counting

Read Abstract +

Proceedings Article | 23 February 2009 Paper

Paper

Fast-gated single-photon avalanche diode for extremely wide dynamic-range applications

A. Tosi, A. Dalla Mora, F. Zappa, S. Cova, D. Contini, A. Pifferi, L. Spinelli, A. Torricelli, R. Cubeddu

Proceedings Volume 7170, 71700K (2009) https://doi.org/10.1117/12.809205

KEYWORDS: Picosecond phenomena, Sensors, Imaging spectroscopy, Pulsed laser operation, Tissue optics, Pulse generators, Tissues, Avalanche photodiodes, Signal detection, Silicon

Read Abstract +

Proceedings Article | 23 February 2009 Paper

Paper

Brain functional imaging at small source-detector distances based on fast-gated single-photon avalanche diodes

Lorenzo Spinelli, Davide Contini, Rinaldo Cubeddu, Antonio Pifferi, Alessandro Torricelli, Fabrizio Martelli, Giovanni Zaccanti, Alberto Tosi, Alberto Dalla Mora, Franco Zappa, Sergio Cova

Proceedings Volume 7161, 71613B (2009) https://doi.org/10.1117/12.808245

KEYWORDS: Picosecond phenomena, Photons, Numerical simulations, Brain, Avalanche photodiodes, Electronics, Optical properties, Tissue optics, Silicon, Monte Carlo methods

Read Abstract +

Proceedings Article | 26 January 2009 Paper

Paper

InGaAs/InP single-photon avalanche diodes show low dark counts and require moderate cooling

A. Tosi, A. Dalla Mora, F. Zappa, S. Cova, M. Itzler, X. Jiang

Proceedings Volume 7222, 72221G (2009) https://doi.org/10.1117/12.808262

KEYWORDS: Avalanche photodiodes, Sensors, Absorption, Photon counting, Single photon detectors, Indium gallium arsenide, Single photon, Photodetectors, Time correlated photon counting, Picosecond phenomena

Read Abstract +

Proceedings Article | 15 October 2007 Open Access

Open Access

Paper

Germanium and InGaAs/InP SPADs for single-photon detection in the near-infrared

Alberto Tosi, Alberto Dalla Mora, Franco Zappa, Sergio Cova

Proceedings Volume 6771, 67710P (2007) https://doi.org/10.1117/12.734961

KEYWORDS: Germanium, Avalanche photodetectors, Indium gallium arsenide, Single photon detectors, Photodetectors, Absorption, Picosecond phenomena, Sensors, Avalanche photodiodes, Near infrared

Read Abstract +

Proceedings Article | 15 October 2007 Paper

Paper

Time-gated single-photon avalanche diode for time-resolved diffuse reflectance at small source-detector separation

Alessandro Torricelli, Antonio Pifferi, Loreno Spinelli, Davide Contini, Rinaldo Cubeddu, Alberto Tosi, Alberto Dalla Mora, Franco Zappa, Sergio Cova

Proceedings Volume 6771, 67710J (2007) https://doi.org/10.1117/12.731778

KEYWORDS: Reflectivity, Avalanche photodiodes, Photodetectors, Diffuse reflectance spectroscopy, Picosecond phenomena, Absorption, Solids, Spatial resolution, Tissue optics, Scattering

Read Abstract +

Proceedings Article | 17 July 2007 Paper

Paper

Time-resolved diffuse reflectance at small source-detector separation using a time-gated single-photon avalanche diode

Antonio Pifferi, Alessandro Torricelli, Lorenzo Spinelli, Davide Contini, Rinaldo Cubeddu, Fabrizio Martelli, Giovanni Zaccanti, Alberto Tosi, Alberto Dalla Mora, Franco Zappa, Sergio Cova

Proceedings Volume 6631, 66310B (2007) https://doi.org/10.1117/12.727947

KEYWORDS: Reflectivity, Avalanche photodiodes, Picosecond phenomena, Photodetectors, Diffuse reflectance spectroscopy, Tissue optics, Absorption, Pulsed laser operation, Solids, Spatial resolution

Read Abstract +

Showing 5 of 88 publications

SIGN IN TO:

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Advertisement

Advertisement