Dr. Brian S. Sorg Profile

Dr. Brian S. Sorg

Program Director at National Cancer Institute

SPIE Involvement:

Author

Publications (26)

Proceedings Article | 6 March 2015 Paper

3D printed biomimetic vascular phantoms for assessment of hyperspectral imaging systems

Jianting Wang, Pejhman Ghassemi, Anthony Melchiorri, Jessica Ramella-Roman, Scott Mathews, James Coburn, Brian Sorg, Yu Chen, Joshua Pfefer

Proceedings Volume 9325, 932508 (2015) https://doi.org/10.1117/12.2084720

KEYWORDS: 3D printing, Imaging systems, 3D image processing, Reflectivity, Printing, Yeast, Hyperspectral imaging, Image segmentation, Tissues, Oximetry

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SPIE Journal Paper | 20 June 2014

Forecasting new development of tumor areas using spatial and temporal distribution profiles of hemoglobin saturation in a mouse model

Miguel Ossandon, Dhananjay Phatak, Brian Sorg, Konstantinos Kalpakis

JMI, Vol. 1, Issue 01, 014503, (June 2014) https://doi.org/10.1117/12.10.1117/1.JMI.1.1.014503

KEYWORDS: Tumors, Image segmentation, Mouse models, Cancer, Image registration, Mode conditioning cables, Tissues, Luminescence, Image analysis, Image transmission

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SPIE Journal Paper | 5 June 2012 Open Access

Comparative evaluation of differential laser-induced perturbation spectroscopy as a technique to discriminate emerging skin pathology

Raymond Kozikowski, Sarah Smith, Jennifer Lee, William Castleman, Brian Sorg, David Hahn

JBO, Vol. 17, Issue 06, 067002, (June 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.6.067002

KEYWORDS: Luminescence, Pathology, Skin, Laser induced fluorescence, Fluorescence spectroscopy, Laser spectroscopy, Spectroscopy, Tissues, Tissue optics, In vivo imaging

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Proceedings Article | 16 February 2012 Paper

In vivo spectral and fluorescence imaging microscopy of tumor microvessel blood supply and oxygenation changes following vascular targeting agent treatment

Jennifer Lee, Raymond Kozikowski, Nikolett Molnar, Dietmar Siemann, Brian Sorg

Proceedings Volume 8222, 82220P (2012) https://doi.org/10.1117/12.905113

KEYWORDS: Tumors, Blood, Luminescence, Blood circulation, In vivo imaging, Veins, Hyperspectral imaging, Microscopy, Animal model studies, Arteries

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Proceedings Article | 9 February 2012 Paper

Delayed photolysis of liposomes: a strategy for the precision timing of bolus drug release using ex-vivo photochemical sensitization

Raymond Kozikowski, Brian Sorg

Proceedings Volume 8221, 82211I (2012) https://doi.org/10.1117/12.909071

KEYWORDS: Photolysis, In vitro testing, Tumors, In vivo imaging, Tissue optics, Blood, Tissues, Data modeling, Cancer, Toxicity

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Proceedings Article | 8 February 2011 Paper

Widefield in vivo spectral and fluorescence imaging microscopy of microvessel blood supply and oxygenation

Jennifer Lee, Raymond Kozikowski, Mamta Wankhede, Brian Sorg

Proceedings Volume 7902, 790209 (2011) https://doi.org/10.1117/12.875363

KEYWORDS: Tumors, Blood, Veins, Blood circulation, Luminescence, Tissues, Arteries, Cancer, Oxygen, In vivo imaging

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Proceedings Article | 17 February 2010 Paper

In vivo 3D and Doppler OCT imaging using electrothermal MEMS scanning mirrors

Jingjing Sun, Shuguang Guo, Lei Wu, Se-Woon Choe, Brian Sorg, Huikai Xie

Proceedings Volume 7594, 759405 (2010) https://doi.org/10.1117/12.847237

KEYWORDS: Optical coherence tomography, Microelectromechanical systems, Mirrors, Actuators, Doppler tomography, In vivo imaging, 3D image processing, Endoscopy, Ear, Cancer

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SPIE Journal Paper | 1 January 2010 Open Access

Spectral imaging reveals microvessel physiology and function from anastomoses to thromboses

Mamta Wankhede, Nikita Agarwal, Rodrigo Fraga-Silva, Casey deDeugd, Mohan Raizada, Suh Oh, Brian Sorg

JBO, Vol. 15, Issue 01, 011111, (January 2010) https://doi.org/10.1117/12.10.1117/1.3316299

KEYWORDS: Tumors, Imaging spectroscopy, Blood circulation, Physiology, Imaging systems, Oxygen, Wound healing, Tissues, Blood, Hypoxia

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Proceedings Article | 25 April 2009 Paper

Spectral and fluorescence imaging of immune system and tissue response to an immunogenic agent

Se-woon Choe, Abhinav Acharya, Benjamin Keselowsky, Brian Sorg

Proceedings Volume 7313, 731305 (2009) https://doi.org/10.1117/12.819014

KEYWORDS: Luminescence, Tissues, Imaging systems, Polymers, Surgery, Particles, Imaging spectroscopy, Microscopy, Blood vessels, Control systems

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Proceedings Article | 13 February 2009 Paper

Spectral imaging of microvascular function in a renal cell carcinoma after treatment with a vascular disrupting agent

Mamta Wankhede, Casey deDeugd, Dietmar Siemann, Brian Sorg

Proceedings Volume 7182, 71820D (2009) https://doi.org/10.1117/12.809381

KEYWORDS: Tumors, Imaging spectroscopy, Tissues, Oxygen, Tumor growth modeling, Hyperspectral imaging, Blood, Blood circulation, Radiotherapy, Image resolution

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SPIE Journal Paper | 1 January 2008 Open Access

Spectral imaging facilitates visualization and measurements of unstable and abnormal microvascular oxygen transport in tumors

Brian Sorg, Matthew Hardee, Nikita Agarwal, Benjamin Moeller, Mark Dewhirst

JBO, Vol. 13, Issue 01, 014026, (January 2008) https://doi.org/10.1117/12.10.1117/1.2837439

KEYWORDS: Tumors, Oxygen, Tissues, Imaging spectroscopy, Hypoxia, Visualization, Imaging systems, Blood circulation, Blood, Microscopes

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Proceedings Article | 21 February 2006 Paper

Optical imaging measurements of oxygen transport fluctuations and gradients in tumor microvascular networks

Brian Sorg, Matthew Hardee, Benjamin Moeller, Mark Dewhirst

Proceedings Volume 6088, 608807 (2006) https://doi.org/10.1117/12.644174

KEYWORDS: Tumors, Hypoxia, Oxygen, Tissues, Blood circulation, Optical testing, Optical imaging, Image acquisition, Microscopes, Image filtering

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SPIE Journal Paper | 1 July 2005 Open Access

Hyperspectral imaging of hemoglobin saturation in tumor microvasculature and tumor hypoxia development

Brian Sorg, Benjamin Moeller, Owen Donovan, Yiting Cao, Mark Dewhirst

JBO, Vol. 10, Issue 04, 044004, (July 2005) https://doi.org/10.1117/12.10.1117/1.2003369

KEYWORDS: Tumors, Oxygen, Hypoxia, Green fluorescent protein, Hyperspectral imaging, Blood, Tissues, Luminescence, Imaging systems, In vivo imaging

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Proceedings Article | 23 March 2005 Paper

Measurement of hemoglobin saturation in tumor microvasculature in preclinical models using hyperspectral imaging

Brian Sorg, Benjamin Moeller, Owen Donovan, Yiting Cao, Mark Dewhirst

Proceedings Volume 5694, (2005) https://doi.org/10.1117/12.585520

KEYWORDS: Tumors, Oxygen, Green fluorescent protein, Hypoxia, Hyperspectral imaging, Luminescence, Imaging systems, Blood, Microscopes, Tumor growth modeling

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Proceedings Article | 17 June 2002 Paper

Tissue soldering with biodegradable polymer films: preliminary in-vivo compatibility test

Brian Sorg, Ashley Welch

Proceedings Volume 4609, (2002) https://doi.org/10.1117/12.430664

KEYWORDS: Control systems, In vivo imaging, Tissues, Skin, In vitro testing, Polymers, Laser welding, Polymer thin films, Natural surfaces, Laser tissue interaction

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Proceedings Article | 21 May 2001 Paper

Tissue soldering with biodegradable polymer films: in-vitro investigation of hydration effects on weld strength

Brian Sorg, Ashley Welch

Proceedings Volume 4244, (2001) https://doi.org/10.1117/12.427788

KEYWORDS: Tissues, Natural surfaces, Polymer thin films, Polymers, Liquids, In vitro testing, Laser welding, Particles, Reflection, Molybdenum

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SPIE Journal Paper | 1 January 2001 Open Access

Improved vascular tissue fusion using new light-activated surgical adhesive on a canine model

Karen McNally-Heintzelman, Brian Sorg, Daniel Hammer, Douglas Heintzelman, Diane Hodges, Ashley Welch

JBO, Vol. 6, Issue 01, (January 2001) https://doi.org/10.1117/12.10.1117/1.1332776

KEYWORDS: Polymers, Proteins, Arteries, Adhesives, Laser tissue interaction, Tissues, Laser welding, Veins, Laser applications, Tissue optics

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Proceedings Article | 17 May 2000 Paper

Biodegradable polymer thin film for enhancement of laser-assisted incision closure with an indocyanine-green-doped liquid albumin solder

Brian Sorg, Karen McNally-Heintzelman, Ashley Welch

Proceedings Volume 3907, (2000) https://doi.org/10.1117/12.386282

KEYWORDS: Laser welding, Control systems, Tissues, Natural surfaces, Liquids, Interfaces, Reflection, Polymer thin films, Laser tissue interaction, Semiconductor lasers

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Proceedings Article | 17 May 2000 Paper

Improved laser-assisted vascular tissue fusion using solder-doped polymer membranes on a canine model

Karen McNally-Heintzelman, Brian Sorg, Daniel Hammer, Douglas Heintzelman, Diane Hodges, Ashley Welch

Proceedings Volume 3907, (2000) https://doi.org/10.1117/12.386230

KEYWORDS: Polymers, Proteins, Laser tissue interaction, Arteries, Laser welding, Adhesives, Tissues, Veins, Semiconductor lasers, Particles

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Proceedings Article | 28 April 2000 Paper

Influence of optical absorption on urinary calculus threshold fluence and ablation efficiency during infrared laser ablation

Kin Foong Chan, Daniel Hammer, Bernard Choi, Gracie Vargas, Brian Sorg, T. Joshua Pfefer, Joel Teichman, H. Stan McGuff, Hans Pratisto, E. Duco Jansen, Ashley Welch

Proceedings Volume 3925, (2000) https://doi.org/10.1117/12.384253

KEYWORDS: Laser ablation, Absorption, Calculi, Laser damage threshold, Tissue optics, Calculus, Absorbance, Hard tissue optics, Free electron lasers, Infrared radiation

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Proceedings Article | 28 April 2000 Paper

Free-electron laser tissue-soldering in vitro with an albumin solder

Brian Sorg, Bernard Choi, Karen McNally-Heintzelman, E. Duco Jansen, Ashley Welch

Proceedings Volume 3925, (2000) https://doi.org/10.1117/12.384257

KEYWORDS: Absorption, Free electron lasers, Laser welding, Laser tissue interaction, Tissues, Chromophores, Natural surfaces, In vitro testing, Infrared radiation, Proteins

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Proceedings Article | 22 June 1999 Paper

Precision dispensing of small volumes of albumin solder for laser-assisted wound closure

Brian Sorg, Karen McNally-Heintzelman, Eric Chan, Christopher Frederickson, Ashley Welch

Proceedings Volume 3590, (1999) https://doi.org/10.1117/12.350950

KEYWORDS: Tissues, Bridges, Laser welding, Natural surfaces, Deposition processes, Semiconductor lasers, Laser tissue interaction, Molybdenum, Pulsed laser operation

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Proceedings Article | 22 June 1999 Paper

ICG-doped albumin protein solders for improved tissue repair

Karen McNally-Heintzelman, Brian Sorg, Ashley Welch, Judith Dawes

Proceedings Volume 3590, (1999) https://doi.org/10.1117/12.350951

KEYWORDS: Proteins, Laser welding, Laser tissue interaction, Tissues, Solids, Liquids, Natural surfaces, Collagen, Semiconductor lasers, Interfaces

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Proceedings Article | 1 July 1998 Paper

Optimal parameters for laser tissue soldering

Karen McNally-Heintzelman, Brian Sorg, Eric Chan, Ashley Welch, Judith Dawes, Earl Owen

Proceedings Volume 3245, (1998) https://doi.org/10.1117/12.312299

KEYWORDS: Proteins, Solids, Laser welding, Liquids, Tissues, Laser tissue interaction, Natural surfaces, Temperature metrology, Semiconductor lasers, Laser applications

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Proceedings Article | 18 August 1997 Paper

Effects of compression on human skin optical properties

Eric Chan, Brian Sorg, Dmitry Protsenko, Michael O'Neil, Massoud Motamedi, Ashley Welch

Proceedings Volume 2979, (1997) https://doi.org/10.1117/12.280260

KEYWORDS: Scattering, Transmittance, Absorption, Optical properties, Tissues, Reflectivity, Skin, Tissue optics, Optical testing, Light scattering

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Proceedings Article | 16 June 1997 Paper

Adaptable three-dimensional Monte Carlo modeling of imaged blood vessels in skin

T. Joshua Pfefer, Jennifer Barton, Eric Chan, Mathieu Ducros, Brian Sorg, Thomas Milner, J. Stuart Nelson, Ashley Welch

Proceedings Volume 2975, (1997) https://doi.org/10.1117/12.275468

KEYWORDS: Monte Carlo methods, Tissue optics, Blood vessels, Tissues, 3D modeling, Photon transport, Skin, Optical simulations, Data modeling, Absorption

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