The results of measurements of transmittance of high power laser irradiation through skull bones and scalp are presented. Dependences of transmittance on sample thickness were received. Character of transmittance was investigated and characteristics of heterogeneity of the scattering structure of the skull bones are proposed. Besides that, variation of temperature of skull and scalp surfaces under exposure of high power laser irradiation during experiments was controlled. Experimental results were verified by Monte-Carlo simulations.
Based on experimental data, obtained in vitro from reflectance measurements and in vivo from digital analysis of color images of human irises, melanin content in human and bovine eye irises has been estimated. Reflectance measurements have been performed using commercially available optical multichannel spectrometer LESA-5 (BioSpec, Russia). For registration of color images digital camera Olympus C-5060 has been used. Analysis of the reflectance spectra has been performed by the method used for determination of melanin content in skin. For digital analysis of iris color images, decomposition of the images in RGB-color-coordinate system has been performed. The images have been obtained both from irises of health volunteers as from irises of patients with glaucoma. Original computer program based on Mathcad software has been developed for the analysis. The results obtained from spectral and color measurements have a good agreement each to other. In eye irises of patients with glaucoma, smaller melanin content has been obtained, and the result has been useful for development of novel and optimization of already existing methods of glaucoma diagnostics.
The main idea of our work is studying of human brain activity for intense NIR-radiation, cold stress or visual stimulation. For the first part of solution we need to find the power density, which needed for brain response observation. For this, we created Monte-Carlo simulation software and make a comparing with out experimental data.
In this paper, we described our results of Monte-Carlo simulation of light propagation in a multi-layered biological tissue, such as the human brain and the skin with optical clearing. The main goal of our simulation was a study of a time delay of the detected signal and the signal form. This report includes optical clearing simulation with some variants of clearing tissue structure. As well as we described general principles of our algorithms construction.
In this paper, we described our results of Monte Carlo simulation of light propagation in a multilayered biological tissue, such as skin with blood layer inclusion and optical clearing. This report includes optical clearing simulations with different variants of clearing tissue structure and different effects, which concerned with optical clearing and blood layer inclusion. As well, we described general principles of our algorithms construction.
KEYWORDS: Skin, Photons, Scattering, Monte Carlo methods, In vivo imaging, Light scattering, Sensors, Temperature metrology, Computer simulations, Tissues
Optical and hystological human skin properties will be over viewed. Experimental set up for in vivo controlling of the skin state will be described. The results of in vivo measurements for the normal and variously treated skin will be presented. Chemical agents and thermal treatment is used in our experiment as the source of skin properties changes. The results of Monte Carlo modeling will also be presented and compared with those of the in vivo experiment.
In this paper, we described our results of Monte-Carlo simulation of light propagation in a multi-layered biological tissue, such as the human brain and the skin with optical clearing. This report includes optical clearing simulations with different variants of clearing tissue structure. As well as we described light beam deformation in a multi-layered tissue and general principles of our algorithms construction.
In this paper, we described our results of computer simulations of light propagation in a multi-layered biological tissue, such as the human brain and the skin. This report includes optical clearing simulations and light propagation researches at small distances. As well as we described light beam deformation in a multi-layered tissue and general principles of our algorithms construction.
In this paper, we described our results of computer simulations of light propagation in a multi-layer biological tissue, such as the human brain and the skin. This report includes description of optical properties of cerebral tissue and skin tissue, some technical characteristics of near-IR noninvasive techniques of the human brain and skin examination. As well as we described light beam deformation in a multi-layer tissue and general principles of our algorithms construction.
In this paper, we described of methods of noninvasive study of the human brain. This overview includes description of optical properties of cerebral tissue, technical characteristics of noninvasive techniques of the human brain examination, such as temporal and spatial resolution, optimal optical parameter for optical imaging, etc. We also touch upon a subject of visual simulation in the optical imaging of the human brain and correlation of brain electrical activity and optical imaging.
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