Dr. Fenghua Tian Profile

Dr. Fenghua Tian

SPIE Involvement:

Author

Area of Expertise:

Diffuse optical imaging , Tissue optics , Near Infrared Spectroscopy , Biomedical instrumentation

Websites:

Company Website

Profile Summary

Dr. Fenghua Tian received his doctoral degree in biomedical engineering from Tsinghua University, Beijing, China in 2003. Then he received postdoctoral training at the University of Pennsylvania (Dr. Britton Chance's lab) and at the Tufts University. Currently he is a research faculty at Department of Bioengineering, the University of Texas At Arlington. His research interests include optical neuroimaging, cerebrovascular and cardiovascular functions, and bedside neuroprotection. The technologies used in his research include near-infrared spectroscopy (NIRS), diffuse optical tomography (DOT), diffuse correlation spectroscopy (DCS), transcranial Doppler (TCD), and so on.

Publications (25)

SPIE Journal Paper | 18 February 2022 Open Access

Open Access

Consistency of children’s hemodynamic responses during spontaneous speech

Seth Tichenor, Bridget Walsh, Katelyn Gerwin, Fenghua Tian

NPh, Vol. 9, Issue 01, 015003, (February 2022) https://doi.org/10.1117/12.10.1117/1.NPh.9.1.015003

KEYWORDS: Image segmentation, Hemodynamics, Brain, Neurophotonics, Neuroimaging, Control systems, Sensors, Picosecond phenomena, Near infrared spectroscopy, Magnetic resonance imaging

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Significance: Hemodynamic responses (HRs) are typically averaged across experimental sessions based on the assumption that brain activation is consistent over multiple trials. This may not be a safe assumption, especially in pediatric populations, due to unaccounted effects of inattention, fatigue, or habituation. Aim: The purpose of this study was to quantify the consistency of the HR over speech and language brain regions during speech production in typically developing school-aged children. Approach: Brain activity over speech and language regions of interest (ROIs) was recorded with functional near-infrared spectroscopy during a picture description paradigm with 37 children (aged 7 to 12 years). We divided the 30 experimental trials, each 5 s long, into three segments of 10 trials each corresponding with early (trials 1 to 10), middle (trials 11 to 20), and late (trials 21 to 30) trials. We then compared oxygenated (HbO) and deoxygenated (HbR) hemoglobin concentrations averaged across each 10 trial segment to overall concentrations averaged across all 30 trials. We also compared differential hemoglobin (HbD) across ROIs. Results: HbO and HbR averaged across all experimental trials most strongly correlated with HbO and HbR from early trials. HbD values from channels over most speech and language regions did not appreciably change throughout the experimental session. The exception was HbD values from channels over the dorsal inferior frontal gyrus (dIFG). This region showed significantly higher activation over the left hemisphere during the first segment of the experiment. Conclusions: Our findings suggest that brain activity from speech and language ROIs was relatively consistent over the experimental session. The exception was increased activation of left dIFG during earlier experimental trials. We suggest that researchers critically evaluate the consistency of HRs from different brain regions to determine the reliability of HRs recorded during experimental sessions. This step is instrumental in ensuring that uncontrolled effects do not mask patterns of task-related activation.

Proceedings Article | 10 March 2020 Presentation

Presentation

Effects of wavelength on transcranial laser stimulation: a Monte Carlo simulation study based on standard brain model (Conference Presentation)

Fenghua Tian, Jenson Varghese, Anh Tran, Qianqian Fang, Francisco Gonzalez-Lima

Proceedings Volume 11221, 112210B (2020) https://doi.org/10.1117/12.2545286

KEYWORDS: Brain, Monte Carlo methods, Tissues, Photon transport, Scattering, Absorption, Neurons, Energy efficiency, Magnetic resonance imaging, Computer simulations

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SPIE Journal Paper | 19 August 2017 Open Access

Open Access

Impairment of cerebral autoregulation in pediatric extracorporeal membrane oxygenation associated with neuroimaging abnormalities

Fenghua Tian, Michael Craig Morriss, Lina Chalak, Ramgopal Venkataraman, Chul Ahn, Hanli Liu, Lakshmi Raman

NPh, Vol. 4, Issue 04, 041410, (August 2017) https://doi.org/10.1117/12.10.1117/1.NPh.4.4.041410

KEYWORDS: Neuroimaging, Magnetic resonance imaging, Brain mapping, Neurophotonics, Wavelets, Ultrasonography, Injuries, Brain, Blood, Computed tomography

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Proceedings Article | 19 April 2017 Presentation

Presentation

Trans-cranial infrared laser stimulation induces hemodynamic and metabolic response measured by broadband near infrared spectroscopy in vivo on human forehead (Conference Presentation)

Xinlong Wang, Sahil Sunil Nalawade, Divya Dhandapani Reddy, Fenghua Tian, F. Gonzalez-Lima, Hanli Liu

Proceedings Volume 10062, 100620M (2017) https://doi.org/10.1117/12.2253496

KEYWORDS: Oxygen, Infrared lasers, Hemodynamics, Near infrared spectroscopy, In vivo imaging, Infrared radiation, Light emitting diodes, Nondestructive evaluation, Brain, Electron transport

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Proceedings Article | 17 February 2017 Presentation + Paper

Presentation + Paper

Diffuse correlation spectroscopy (DCS) study of blood flow changes during low level laser therapy (LLLT): a preliminary report

Sagar Soni, Xinlong Wang, Hanli Liu, Fenghua Tian

Proceedings Volume 10048, 1004806 (2017) https://doi.org/10.1117/12.2252604

KEYWORDS: Spectroscopy, Laser therapeutics, Hemodynamics, Tissues, In vivo imaging, Oxygen, Sensors, Skin, Near infrared spectroscopy

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SPIE Journal Paper | 19 December 2016 Open Access

Open Access

Prefrontal hemodynamic mapping by functional near-infrared spectroscopy in response to thermal stimulations over three body sites

Amarnath Yennu, Fenghua Tian, Robert Gatchel, Hanli Liu

NPh, Vol. 3, Issue 04, 045008, (December 2016) https://doi.org/10.1117/12.10.1117/1.NPh.3.4.045008

KEYWORDS: Solids, Staring arrays, Hemodynamics, Near infrared spectroscopy, Barium, Sensors, Neurophotonics, Functional magnetic resonance imaging, Brain, Statistical analysis

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SPIE Journal Paper | 21 April 2015 Open Access

Open Access

Evaluation of cortical plasticity in children with cerebral palsy undergoing constraint-induced movement therapy based on functional near-infrared spectroscopy

Jianwei Cao, Bilal Khan, Nathan Hervey, Fenghua Tian, Mauricio Delgado, Nancy Clegg, Linsley Smith, Heather Roberts, Kirsten Tulchin-Francis, Angela Shierk, Laura Shagman, Duncan MacFarlane, Hanli Liu, George Alexandrakis

JBO, Vol. 20, Issue 04, 046009, (April 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.4.046009

KEYWORDS: Sensors, Control systems, Hemodynamics, Sensorimotor cortex, Brain, Near infrared spectroscopy, Functional magnetic resonance imaging, Signal to noise ratio, Cortical activation, Bandpass filters

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Proceedings Article | 10 March 2015 Paper

Paper

FNIRS-based evaluation of cortical plasticity in children with cerebral palsy undergoing constraint-induced movement therapy

Jianwei Cao, Bilal Khan, Nathan Hervey, Fenghua Tian, Mauricio Delgado, Nancy Clegg, Linsley Smith, Heather Roberts, Kirsten Tulchin-Francis, Angela Shierk, Laura Shagman, Duncan MacFarlane, Hanli Liu, George Alexandrakis

Proceedings Volume 9305, 93050N (2015) https://doi.org/10.1117/12.2076995

KEYWORDS: Control systems, Sensors, Sensorimotor cortex, Neuroimaging, Functional magnetic resonance imaging, Signal to noise ratio, Brain, Near infrared spectroscopy, Hemodynamics, Magnetic resonance imaging

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SPIE Journal Paper | 11 November 2014 Open Access

Open Access

Motion tracking and electromyography-assisted identification of mirror hand contributions to functional near-infrared spectroscopy images acquired during a finger-tapping task performed by children with cerebral palsy

Nathan Hervey, Bilal Khan, Laura Shagman, Fenghua Tian, Mauricio Delgado, Kirsten Tulchin-Francis, Angela Shierk, Heather Roberts, Linsley Smith, Dahlia Reid, Nancy Clegg, Hanli Liu, Duncan MacFarlane, George Alexandrakis

NPh, Vol. 1, Issue 02, 025009, (November 2014) https://doi.org/10.1117/12.10.1117/1.NPh.1.2.025009

KEYWORDS: Mirrors, Electromyography, Independent component analysis, Brain, Near infrared spectroscopy, Sensors, Hemodynamics, Motion models, Neuroimaging, Neurophotonics

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Proceedings Article | 25 March 2013 Paper

Paper

EasyTopo: A toolbox for rapid diffuse optical topography based on a standard template of brain atlas

Fenghua Tian, Zi-Jing Lin, Hanli Liu

Proceedings Volume 8578, 85782J (2013) https://doi.org/10.1117/12.2003907

KEYWORDS: Brain, Sensors, Spherical lenses, Brain activation, Absorption, Neuroimaging, Image sensors, Geometrical optics, Tomography, Inverse optics

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Proceedings Article | 8 March 2013 Paper

Paper

Motion tracking and electromyography assist the removal of mirror hand contributions to fNIRS images acquired during a finger tapping task performed by children with cerebral palsy

Nathan Hervey, Bilal Khan, Laura Shagman, Fenghua Tian, Mauricio Delgado, Kirsten Tulchin-Francis, Angela Shierk, Linsley Smith, Dahlia Reid, Nancy Clegg, Hanli Liu, Duncan MacFarlane, George Alexandrakis

Proceedings Volume 8565, 856563 (2013) https://doi.org/10.1117/12.2004352

KEYWORDS: Mirrors, Electromyography, Motion measurement, Kinematics, Hemodynamics, Filtering (signal processing), Brain, Motion analysis, Sensors, Linear filtering

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SPIE Journal Paper | 7 November 2012 Open Access

Open Access

Test-retest assessment of cortical activation induced by repetitive transcranial magnetic stimulation with brain atlas-guided optical topography

Fenghua Tian, F. Andrew Kozel, Amarnath Yennu, Paul Croarkin, Shawn McClintock, Kimberly Mapes, Mustafa Husain, Hanli Liu

JBO, Vol. 17, Issue 11, 116020, (November 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.11.116020

KEYWORDS: Brain, Reliability, Magnetism, Hemodynamics, Prefrontal cortex, Cortical activation, Neuroimaging, Spherical lenses, Head, Data analysis

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SPIE Journal Paper | 1 April 2011 Open Access

Open Access

Resting-state functional connectivity assessed with two diffuse optical tomographic systems

Haijing Niu, Chun-Ming Lu, Chaozhe Zhu, Sabin Khadka, Fenghua Tian, Zi-Jing Lin, Hanli Liu

JBO, Vol. 16, Issue 04, 046006, (April 2011) https://doi.org/10.1117/12.10.1117/1.3561687

KEYWORDS: Imaging systems, Hemodynamics, Tomography, Brain, Sensorimotor cortex, Biomedical optics, Sensors, Near infrared spectroscopy, Functional magnetic resonance imaging, Near infrared

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Proceedings Article | 1 March 2011 Paper

Paper

Investigation of cerebral hemodynamic changes during repeated sit-stand maneuver using functional near-infrared spectroscopy

Haijing Niu, Lin Li, Gauri Bhave, Zi-jing Lin, Fenghua Tian, Behbehani Khosrow, Rong Zhang, Hanli Liu

Proceedings Volume 7898, 78980R (2011) https://doi.org/10.1117/12.875944

KEYWORDS: Hemodynamics, Signal detection, Cerebral blood flow, Brain, Near infrared spectroscopy, Arteries, Sensors, Prefrontal cortex, Blood circulation, Functional near infrared spectroscopy

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Proceedings Article | 18 February 2011 Paper

Paper

Functional near infrared brain imaging with a brush-fiber optode to improve optical contact on subjects with dense hair

Bilal Khan, Chester Wildey, Robert Francis, Fenghua Tian, Mario Romero, Mauricio Delgado, Nancy Clegg, Linsley Smith, Hanli Liu, Duncan MacFarlane, George Alexandrakis

Proceedings Volume 7883, 78834V (2011) https://doi.org/10.1117/12.873839

KEYWORDS: Signal detection, Signal attenuation, Signal to noise ratio, Monte Carlo methods, Sensors, Tissue optics, Near infrared, Hemodynamics, Human subjects, Photon transport

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Proceedings Article | 18 February 2011 Paper

Paper

Identification of prefrontal cortex (BA10) activation while performing Stroop test using diffuse optical tomography

Sabin Khadka, Srujan Chityala, Fenghua Tian, Hanli Liu

Proceedings Volume 7883, 78834B (2011) https://doi.org/10.1117/12.875957

KEYWORDS: Prefrontal cortex, Brain, Targeting Task Performance metric, Hemodynamics, Promethium, Diffuse optical tomography, Signal detection, Optical testing, Brain mapping, Positron emission tomography

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Proceedings Article | 17 February 2011 Paper

Paper

Algorithmic depth compensation improves transverse resolution and quantification in functional diffuse optical tomography

Fenghua Tian, Haijing Niu, Sabin Khadka, Zi-Jing Lin, Hanli Liu

Proceedings Volume 7896, 78960N (2011) https://doi.org/10.1117/12.875835

KEYWORDS: Absorption, Reconstruction algorithms, Spatial resolution, Diffuse optical tomography, Tissues, Image resolution, Algorithm development, Distortion, Sensors, Scattering

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SPIE Journal Paper | 1 July 2010 Open Access

Open Access

Comprehensive investigation of three-dimensional diffuse optical tomography with depth compensation algorithm

Haijing Niu, Zijing Lin, Fenghua Tian, Sameer Dhamne, Hanli Liu

JBO, Vol. 15, Issue 04, 046005, (July 2010) https://doi.org/10.1117/12.10.1117/1.3462986

KEYWORDS: Absorption, Spatial resolution, Diffuse optical tomography, 3D image processing, Tissues, Image quality, Brain, Brain imaging, 3D image reconstruction, Computer simulations

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SPIE Journal Paper | 1 May 2010 Open Access

Open Access

Identification of abnormal motor cortex activation patterns in children with cerebral palsy by functional near-infrared spectroscopy

Bilal Khan, Fenghua Tian, Khosrow Behbehani, Mario Romero-Ortega, Mauricio Delgado, Nancy Clegg, Linsley Smith, Dahlia Reid, Hanli Liu, George Alexandrakis

JBO, Vol. 15, Issue 03, 036008, (May 2010) https://doi.org/10.1117/12.10.1117/1.3432746

KEYWORDS: Control systems, Electronic filtering, Digital filtering, Image processing, Hemodynamics, Sensors, Near infrared spectroscopy, Brain, Electromyography, Functional magnetic resonance imaging

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SPIE Journal Paper | 1 September 2009 Open Access

Open Access

Investigation of the prefrontal cortex in response to duration-variable anagram tasks using functional near-infrared spectroscopy

Fenghua Tian, Britton Chance, Hanli Liu

JBO, Vol. 14, Issue 05, 054016, (September 2009) https://doi.org/10.1117/12.10.1117/1.3241984

KEYWORDS: Hemodynamics, Functional magnetic resonance imaging, Brain, Prefrontal cortex, Superposition, Near infrared spectroscopy, Nonlinear optics, Data analysis, Wavelets, Continuous wavelet transforms

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Proceedings Article | 25 February 2009 Paper

Paper

Translation of near infrared brain imaging to assess children with cerebral palsy

George Alexandrakis, Bilal Khan, Fenghua Tian, Nayan Asanani, Khosrow Behbehani, Mauricio Delgado, Hanli Liu

Proceedings Volume 7180, 718005 (2009) https://doi.org/10.1117/12.809340

KEYWORDS: Electronic filtering, Filtering (signal processing), Signal detection, Hemodynamics, Digital filtering, Brain, Signal processing, Image filtering, Sensors, Data acquisition

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Proceedings Article | 23 February 2009 Paper

Paper

Bilateral responses of prefrontal and motor cortices to repetitive transcranial magnetic stimulation as measured by functional near infrared spectroscopy

Fenghua Tian, Frank Andrew Kozel, Sameer Dhamne, Shawn McClintock, Paul Croarkin, Kimberly Mapes, Mustafa Husain, Hanli Liu

Proceedings Volume 7161, 71613C (2009) https://doi.org/10.1117/12.809343

KEYWORDS: Prefrontal cortex, Hemodynamics, Brain, Magnetism, Functional near infrared spectroscopy, Sensors, Data acquisition, Tissues, Near infrared, Statistical analysis

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Proceedings Article | 23 February 2009 Paper

Paper

Investigation of the prefrontal cortex in response to duration-variable anagram tasks using functional near infrared spectroscopy

Fenghua Tian, Britton Chance, Hanli Liu

Proceedings Volume 7161, 71613J (2009) https://doi.org/10.1117/12.809591

KEYWORDS: Superposition, Hemodynamics, Functional magnetic resonance imaging, Nonlinear optics, Prefrontal cortex, Functional near infrared spectroscopy, Systems modeling, Solids, Sensors, Ear

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Proceedings Article | 18 January 2005 Paper

Paper

Using noninvasive NIRS to evaluate the metabolic capability of infant brain

Lan Huang, Haishu Ding, Xinling Hou, Congle Zhou, Zhiguang Lie, Guangzhi Wang, Fenghua Tian

Proceedings Volume 5630, (2005) https://doi.org/10.1117/12.575905

KEYWORDS: Oxygen, Near infrared spectroscopy, Tissue optics, Brain, Sensors, Hypoxia, Mode conditioning cables, Tissues, Biomedical optics, Light sources

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Proceedings Article | 12 April 2002 Paper

Paper

Near-infrared spectroscopic assessment of oxygen delivery to free flaps on monkeys following vascular occlusions and inhalation of pure oxygen

Fenghua Tian, Haishu Ding, Zhigang Cai, Guangzhi Wang, Fuyun Zhao

Proceedings Volume 4536, (2002) https://doi.org/10.1117/12.462567

KEYWORDS: Oxygen, Near infrared spectroscopy, Surgery, Tissues, Tissue optics, Optical fibers, Spectroscopy, Absorption, Absorbance, Reflectivity

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Showing 5 of 25 publications

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