A localized surface plasmon resonance (LSPR) based optical fiber biosensor using gold nanorods has been developed.
The LSPR optical fiber sensor was fabricated by immobilizing gold nanorods at the distal end of a multimode fiber. The
surface of gold nanorods was further functionalized with human IgG to create a biosensor to detect anti-human IgG. The
peak shift of the longitudinal plasmon wavelength of gold nanorod was monitored as a function of the refractive index
change. The results show that refractive index sensitivity of this sensor is 506 nm/RIU, and the limit of detection for antihuman
IgG is 3 nM.
A localized surface plasmon resonance (LSPR) based optical fibre sensor using gold nanorods has been demonstrated,
showing a much higher sensitivity to the refractive index change surrounding the sensing area than that using gold
nanoparticles. In this work, a novel method has been employed to improve gold nanorod synthesis and immobilization
on the exposed surface area of an optical fibre core intended for sensor use. The device sensitivity, measured as a
function of the refractive index change, was found to be around 778nm/RIU (RIU=Refractive Index Unit), showing
considerable promise to be a better platform for label-free biosensors, monitoring the interaction between antibodies and
their antigens in a number of sensing applications in industry.
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