Dr. Julia Walther Profile

Dr. Julia Walther

Lecturer at Universitätsklinikum Carl Gustav Carus Dresden

SPIE Involvement:

Author

Publications (49)

Proceedings Article | 13 March 2024 Presentation

Evaluating caries lesions with polarized and depolarized light techniques

Julia Grundmann, Jonas Golde, Svea Steuer, Florian Tetschke, Lars Kirsten, Edmund Koch, Christian Hannig, Julia Walther

Proceedings Volume PC12845, PC1284503 (2024) https://doi.org/10.1117/12.3001421

KEYWORDS: Dental caries, Polarized light, Polarization, Depolarization, Teeth, Optical properties, Visualization, Tissues, Polarized microscopy, Optical components

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Proceedings Article | 12 March 2024 Presentation + Paper

Depolarization for the assessment of caries in polarized light microscopy

Jonas Golde, Julia Grundmann, Svea Steuer, Florian Tetschke, Lars Kirsten, Edmund Koch, Julia Walther, Christian Hannig

Proceedings Volume 12845, 1284505 (2024) https://doi.org/10.1117/12.3002869

KEYWORDS: Dental caries, Polarization, Polarized light, Depolarization, Teeth, Cameras, Optical coherence tomography, Polarized microscopy, Diagnostics, Tissues

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Proceedings Article | 17 March 2023 Presentation

Interdental detection of proximal caries in vivo by polarization-sensitive optical coherence tomography

Jonas Golde, Michael Hackmann, Qingyun Li, Onur Cetinkaya, Tobias Rosenauer, Florian Tetschke, Christian Schnabel, Karol Karnowski, David Sampson, Edmund Koch, Christian Hannig, Julia Walther

Proceedings Volume PC12356, PC1235602 (2023) https://doi.org/10.1117/12.2648890

KEYWORDS: Optical coherence tomography, Dental caries, In vivo imaging, Radiography, Diagnostics, Teeth, Stereoscopy, Radio optics, Fiber optics, Birefringence

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Proceedings Article | 17 March 2023 Presentation

Noninvasive optical biopsy of human oral lichen planus in vivo by optical coherence tomography

Yuliia Gruda, Jonas Golde, Jiawen Li, Marius Albrecht, Christian Schnabel, Dominik Haim, Guenter Lauer, Korinna Joehrens, Michaela Buckova, Robert McLaughlin, Julia Walther

Proceedings Volume 12354, 123540A (2023) https://doi.org/10.1117/12.2648925

KEYWORDS: Optical coherence tomography, In vivo imaging, Biopsy, Tissues, Medicine, Visualization, Point-of-care devices, Natural surfaces, Medical diagnostics

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Proceedings Article | 7 March 2022 Presentation

Polarization-sensitive OCT using a single-mode fiber-based common-path probe

Jonas Golde, Julia Walther, Jiawen Li, Robert McLaughlin, Edmund Koch

Proceedings Volume PC11948, PC119481B (2022) https://doi.org/10.1117/12.2607184

KEYWORDS: Optical coherence tomography, Polarization, Single mode fibers, Statistical analysis, Signal generators, Scattering, Polarization maintaining fibers, Phase matching, Light scattering, Interferometry

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Proceedings Article | 7 March 2022 Presentation

Clinical imaging of the oral mucosa using a miniaturized intraoral probe for optical coherence tomography

Julia Walther, Jonas Golde, Bryden Quirk, Loretta Scolaro, Rodney Kirk, Marius Abrecht, Yuliia Gruda, Christian Schnabel, Florian Tetschke, Dominik Haim, Michaela Buckova, Jiawen Li, Robert McLaughlin

Proceedings Volume PC11937, PC1193703 (2022) https://doi.org/10.1117/12.2609571

KEYWORDS: Optical coherence tomography, In vivo imaging, Tissues, Visualization, Reflectivity, Optical inspection, Mouth, Microcontrollers, Magnetism, GRIN lenses

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Proceedings Article | 7 March 2022 Poster + Presentation

Manual and semi-automatic measurement of oral epithelial thickness using optical coherence tomography (OCT)

Marius Albrecht, Christian Schnabel, Juliane Mueller, Jonas Golde, Edmund Koch, Julia Walther

Proceedings Volume PC11935, PC119350C (2022) https://doi.org/10.1117/12.2606635

KEYWORDS: Optical coherence tomography, Evolutionary algorithms, In vivo imaging, Image segmentation, Diagnostics, Databases, Artificial intelligence

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Proceedings Article | 7 March 2022 Poster + Presentation

Optical coherence tomography (OCT) for caries diagnosis of proximal tooth surfaces

Ronja Dietrich, Jonas Golde, Florian Tetschke, Tobias Rosenauer, Marie-Theres Weber, Edmund Koch, Christian Hannig, Julia Walther

Proceedings Volume PC11942, PC1194207 (2022) https://doi.org/10.1117/12.2610145

KEYWORDS: Optical coherence tomography, Teeth, Dental caries, Visualization, Diagnostics, Polarization, Optical imaging, X-rays, X-ray imaging, X-ray fluorescence spectroscopy

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Proceedings Article | 9 December 2021 Paper

Polarization-sensitive OCT using a single-mode fiber-based common-path probe

Jonas Golde, Julia Walther, Jiawen Li, Robert McLaughlin, Edmund Koch

Proceedings Volume 11924, 119240W (2021) https://doi.org/10.1117/12.2616063

KEYWORDS: Polarization, Spectroscopy, Optical coherence tomography, Single mode fibers, Mirrors, Birefringence, Poincaré sphere, Tissue optics, Sensors, Scattering

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Proceedings Article | 5 March 2021 Presentation

Optical coherence tomography for the non-invasive structural anatomy of the human oral mucosa

Marius Albrecht, Christian Schnabel, Juliane Müller, Jonas Golde, Edmund Koch, Julia Walther

Proceedings Volume 11627, 1162706 (2021) https://doi.org/10.1117/12.2578280

KEYWORDS: Optical coherence tomography, In vivo imaging, Tissues, Tissue optics, Visualization, Visual analytics, Soft tissue optics, Optical imaging, Optical components, Medical imaging

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Proceedings Article | 9 March 2020 Presentation

Depolarization imaging for caries detection validated by co-registered PS-OCT and µCT volumes (Conference Presentation)

Jonas Golde, Florian Tetschke, Robin Vosahlo, Julia Walther, Christian Hannig, Edmund Koch, Lars Kirsten

Proceedings Volume 11217, 1121707 (2020) https://doi.org/10.1117/12.2546764

KEYWORDS: Dental caries, Teeth, Optical coherence tomography, Polarization, Data acquisition, X-ray microscopy, X-ray imaging, X-rays, Tomography, Polarized microscopy

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Proceedings Article | 19 July 2019 Paper

Endoscopic optical coherence tomography at the middle ear diagnostic

Martin Schindler, Lars Kirsten, Joseph Morgenstern, Jonas Golde, Julia Walther, Max Kemper, Matthias Bornitz, Marcus Neudert, Thomas Zahnert, Edmund Koch

Proceedings Volume 11073, 110731K (2019) https://doi.org/10.1117/12.2527125

KEYWORDS: Optical coherence tomography, Ear, Endoscopy, Diagnostics, Medicine, Imaging systems, GRIN lenses, Cameras, Visualization, Functional imaging

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Proceedings Article | 19 July 2019 Paper

Assessment of occlusal enamel alterations utilizing depolarization imaging based on PS-OCT

Jonas Golde, Florian Tetschke, Robin Vosahlo, Julia Walther, Christian Hannig, Edmund Koch, Lars Kirsten

Proceedings Volume 11078, 110780P (2019) https://doi.org/10.1117/12.2527228

KEYWORDS: Optical coherence tomography, Teeth, Dental caries, Optical inspection, Visualization, Medicine, Inspection, Polarization, Scattering, Dentistry

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Proceedings Article | 13 March 2019 Presentation

Monitoring of artificial incipient enamel lesions with polarization-sensitive optical coherence tomography (Conference Presentation)

Florian Tetschke, Jonas Golde, Sabine Basche, Tobias Rosenauer, Julia Walther, Christian Hannig, Edmund Koch, Lars Kirsten

Proceedings Volume 10857, 1085703 (2019) https://doi.org/10.1117/12.2510441

KEYWORDS: Optical coherence tomography, Polarization, Tissues, Therapeutics, Tissue optics, Dental caries, Microfluidics, Microscopy, Tomography, Minerals

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Proceedings Article | 28 February 2019 Paper

Qualitative image comparison between in vivo endoscopic optical coherence tomography and conventional histology of the healthy human oral mucosa

Marius Albrecht, Christian Schnabel, Edmund Koch, Julia Walther

Proceedings Volume 10857, 1085708 (2019) https://doi.org/10.1117/12.2507767

KEYWORDS: In vivo imaging, Endoscopy, Optical coherence tomography, Digital Light Processing

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SPIE Journal Paper | 4 December 2018 Open Access

Endoscopic optical coherence tomography with wide field-of-view for the morphological and functional assessment of the human tympanic membrane

Lars Kirsten, Martin Schindler, Joseph Morgenstern, Mikael Timo Erkkilä, Jonas Golde, Julia Walther, Pascal Rottmann, Max Kemper, Matthias Bornitz, Marcus Neudert, Thomas Zahnert, Edmund Koch

JBO, Vol. 24, Issue 03, 031017, (December 2018) https://doi.org/10.1117/12.10.1117/1.JBO.24.3.031017

KEYWORDS: Optical coherence tomography, Endoscopy, Ear, Endoscopes, In vivo imaging, Video, Visualization, Gradient-index optics, Doppler tomography, Scanners

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SPIE Journal Paper | 2 March 2018 Open Access

In vivo imaging in the oral cavity by endoscopic optical coherence tomography

Julia Walther, Christian Schnabel, Florian Tetschke, Tobias Rosenauer, Jonas Golde, Nadja Ebert, Michael Baumann, Christian Hannig, Edmund Koch

JBO, Vol. 23, Issue 07, 071207, (March 2018) https://doi.org/10.1117/12.10.1117/1.JBO.23.7.071207

KEYWORDS: Optical coherence tomography, Endoscopy, In vivo imaging, Tissues, Endoscopes, Tissue optics, Teeth, Scanners, Imaging systems, Soft tissue optics

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SPIE Journal Paper | 26 January 2018 Open Access

Detection of carious lesions utilizing depolarization imaging by polarization sensitive optical coherence tomography

Jonas Golde, Florian Tetschke, Julia Walther, Tobias Rosenauer, Franz Hempel, Christian Hannig, Edmund Koch, Lars Kirsten

JBO, Vol. 23, Issue 07, 071203, (January 2018) https://doi.org/10.1117/12.10.1117/1.JBO.23.7.071203

KEYWORDS: Polarization, Optical coherence tomography, Teeth, Dental caries, Reflectivity, Tissues, Medicine, Tissue optics, Visualization, Biomedical optics

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SPIE Journal Paper | 20 December 2017 Open Access

In vivo imaging of human oral hard and soft tissues by polarization-sensitive optical coherence tomography

Julia Walther, Jonas Golde, Lars Kirsten, Florian Tetschke, Franz Hempel, Tobias Rosenauer, Christian Hannig, Edmund Koch

JBO, Vol. 22, Issue 12, 121717, (December 2017) https://doi.org/10.1117/12.10.1117/1.JBO.22.12.121717

KEYWORDS: Optical coherence tomography, Tissues, Polarization, Picosecond phenomena, In vivo imaging, Teeth, Reflectivity, Tissue optics, Soft tissue optics, Optical fibers

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Proceedings Article | 1 August 2017 Paper

Lateral resonant Doppler flow measurement by spectral domain optical coherence tomography

Julia Walther, Edmund Koch

Proceedings Volume 10416, 1041602 (2017) https://doi.org/10.1117/12.2286078

KEYWORDS: Doppler tomography, Optical coherence tomography, Motion analysis, Statistical analysis, Scattering

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Proceedings Article | 1 August 2017 Paper

3D handheld endoscope for optical coherence tomography of the human oral mucosa in vivo

Julia Walther, Christian Schnabel, Nadja Ebert, Michael Baumann, Edmund Koch

Proceedings Volume 10416, 104160F (2017) https://doi.org/10.1117/12.2286073

KEYWORDS: In vivo imaging, Endoscopes, Optical coherence tomography, 3D image processing, Tissue optics, Cancer

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Proceedings Article | 9 July 2015 Paper

Optimal processing of Doppler signals in OCT

Julia Walther, Lars Kirsten, Edmund Koch

Proceedings Volume 9541, 954102 (2015) https://doi.org/10.1117/12.2183444

KEYWORDS: Signal to noise ratio, Optical coherence tomography, Doppler effect, Doppler tomography, Signal processing, Phase shifts, Convolution, Interference (communication), Sensors, Biomedical optics

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Proceedings Article | 9 July 2015 Paper

Imaging the tympanic membrane oscillation ex vivo with Doppler optical coherence tomography during simulated Eustachian catarrh

Lars Kirsten, Anke Burkhardt, Jonas Golde, Julia Walther, Thomas Stoppe, Matthias Bornitz, Max Kemper, Thomas Zahnert, Edmund Koch

Proceedings Volume 9541, 95410R (2015) https://doi.org/10.1117/12.2183620

KEYWORDS: Optical coherence tomography, Doppler tomography, Ear, Visualization, Doppler effect, In vivo imaging, Medicine, Spatial resolution, Diagnostics, Functional imaging

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SPIE Journal Paper | 30 March 2015 Open Access

Imaging of nanoparticle-labeled stem cells using magnetomotive optical coherence tomography, laser speckle reflectometry, and light microscopy

Peter Cimalla, Theresa Werner, Kai Winkler, Claudia Mueller, Sebastian Wicht, Maria Gaertner, Mirko Mehner, Julia Walther, Bernd Rellinghaus, Dierk Wittig, Mike O. Karl, Marius Ader, Richard H. Funk, Edmund Koch

JBO, Vol. 20, Issue 03, 036018, (March 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.3.036018

KEYWORDS: Optical coherence tomography, Magnetism, Particles, Speckle, Nanoparticles, Stem cells, Microscopy, Reflectometry, Tissues, Microscopes

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Proceedings Article | 18 June 2013 Paper

Magnetomotive imaging of iron oxide nanoparticles as cellular contrast agents for optical coherence tomography

Peter Cimalla, Theresa Werner, Maria Gaertner, Claudia Mueller, Julia Walther, Dierk Wittig, Marius Ader, Mike Karl, Edmund Koch

Proceedings Volume 8802, 88020M (2013) https://doi.org/10.1117/12.2032813

KEYWORDS: Optical coherence tomography, Magnetism, Nanoparticles, Tissues, Luminescence, Doppler effect, Phase shifts, Modulation, Oxides, Microscopy

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Proceedings Article | 18 June 2013 Paper

Velocity noise reduction by using enhanced joint spectral and time domain optical coherence tomography

Julia Walther, Edmund Koch

Proceedings Volume 8802, 88020K (2013) https://doi.org/10.1117/12.2032699

KEYWORDS: Optical coherence tomography, Doppler tomography, Doppler effect, Denoising, Velocity measurements, Scanners, Capillaries, Phase shifts, Fourier transforms, Biomedical optics

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SPIE Journal Paper | 16 May 2012 Open Access

Endoscopic optical coherence tomography device for forward imaging with broad field of view

Anke Burkhardt, Julia Walther, Peter Cimalla, Mirko Mehner, Edmund Koch

JBO, Vol. 17, Issue 7, 071302, (May 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.7.071302

KEYWORDS: Optical coherence tomography, GRIN lenses, Endoscopy, Imaging devices, Relays, Imaging systems, Cameras, Gradient-index optics, Tissue optics, In vivo imaging

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Proceedings Article | 30 January 2012 Paper

Resolution improvement in dual-band OCT by filling the spectral gap

Peter Cimalla, Maria Gaertner, Julia Walther, Edmund Koch

Proceedings Volume 8213, 82132M (2012) https://doi.org/10.1117/12.908331

KEYWORDS: Optical coherence tomography, Spectral resolution, Image processing, Spectroscopy, Algorithm development, Image resolution, Imaging systems, Light sources, Phase shifts, Phase measurement

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In most dual-band OCT systems, there is a spectral gap between both bands. This might be as large as one third of the total spectral region. Therefore, a simple Fourier transformation of the data does not give the resolution that could be possible considering the overall spectral width. Instead, the full width of the peak is comparable to the width resulting from a single band and is additionally modulated. We compare several methods to achieve a high resolution in spite of the missing data. Because in a dual-band system the image quality resulting from the full information is not known we test and optimize different algorithms by using the data from a single band system and excluding an equal part of the spectrum. While methods using non-equidistant sample points like Vandermonde and Lomb transformation work well with small spectral gaps, they result in large image artifacts for broader gaps, which are typical for dual-band OCT systems. Simulations show that fitting the available data with a limited set of sine and cosines functions might give good results but for larger gaps and appropriate amount of basis-functions this method fails, too. Dividing both bands into overlapping smaller bands and looking at the phase of short-time Fourier transformations (STFT) resulting from a single scatterer, it becomes clear that the amplitude of all Fourier coefficients for the total band can be estimated by the change of the phase of the STFTs in and between both bands. Therefore, we developed an algorithm of weighting the data based on the phase distribution of the STFT data. As a single value specifying the phase distribution we choose the absolute sum of the STFTs divided by the sum of the amplitudes of the STFTs. Because typical OCT data are not caused by single scatterers, we adapted this algorithm with a cluster analysis to predict the appropriate amplitude expected for a full spectrum from the phase distribution of the STFTs inside both bands and between both bands. Although the image is noisier and fainter compared to an image from the full spectrum, the resulting image has the best resolution from all methods investigated.

SPIE Journal Paper | 1 November 2011 Open Access

Shear flow-induced optical inhomogeneity of blood assessed in vivo and in vitro by spectral domain optical coherence tomography in the 1.3 μm wavelength range

Peter Cimalla, Julia Walther, Matthaeus Mittasch, Edmund Koch

JBO, Vol. 16, Issue 11, 116020, (November 2011) https://doi.org/10.1117/12.10.1117/1.3653235

KEYWORDS: Blood, Optical coherence tomography, Capillaries, Backscatter, Modulation, In vivo imaging, Doppler effect, Blood vessels, Arteries, Double patterning technology

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Proceedings Article | 1 June 2011 Paper

Axial resolution improvement by spectral data fusion in simultaneous dual-band optical coherence tomography

Peter Cimalla, Maria Gaertner, Julia Walther, Edmund Koch

Proceedings Volume 8091, 80911N (2011) https://doi.org/10.1117/12.889740

KEYWORDS: Optical coherence tomography, Spectral resolution, Data fusion, Image resolution, Spectroscopy, Imaging systems, Glasses, Tissues, Light sources, Fourier transforms

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Proceedings Article | 1 June 2011 Paper

Endoscopic optical coherence tomography for imaging the tympanic membrane

Anke Burkhardt, Julia Walther, Peter Cimalla, Matthias Bornitz, Edmund Koch

Proceedings Volume 8091, 80910Y (2011) https://doi.org/10.1117/12.889734

KEYWORDS: Optical coherence tomography, Endoscopy, Scanners, Head, Ear, Coherence imaging, Visualization, Cameras, GRIN lenses, Neodymium

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Proceedings Article | 1 June 2011 Paper

Enhanced joint spectral and time domain optical coherence tomography for quantitative flow velocity measurement

Julia Walther, Edmund Koch

Proceedings Volume 8091, 80910L (2011) https://doi.org/10.1117/12.889685

KEYWORDS: Optical coherence tomography, Doppler tomography, Doppler effect, Capillaries, Signal detection, Velocity measurements, Signal processing, Scattering, Signal analyzers, Phase shifts

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Proceedings Article | 1 June 2011 Paper

Optical coherence tomography for imaging of subpleural alveolar structure using a Fourier domain mode locked laser

Lars Kirsten, Julia Walther, Peter Cimalla, Maria Gaertner, Sven Meissner, Edmund Koch

Proceedings Volume 8091, 809118 (2011) https://doi.org/10.1117/12.889615

KEYWORDS: Optical coherence tomography, Lung, Signal to noise ratio, Mode locking, In vivo imaging, Tissues, Coherence imaging, Single mode fibers, Visualization, Biomedical optics

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Proceedings Article | 12 February 2011 Paper

Lateral resonant Doppler imaging for quantitative flow extraction in spectral domain optical coherence tomography

Julia Walther, Peter Cimalla, Edmund Koch

Proceedings Volume 7889, 788914 (2011) https://doi.org/10.1117/12.874522

KEYWORDS: Doppler tomography, Doppler effect, Optical coherence tomography, Phase shifts, Capillaries, Scanners, Sensors, Backscatter, Statistical modeling, 3D scanning

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Proceedings Article | 5 February 2011 Paper

Non-invasive imaging and monitoring of rodent retina using simultaneous dual-band optical coherence tomography

Peter Cimalla, Anke Burkhardt, Julia Walther, Aline Hoefer, Dierk Wittig, Richard Funk, Edmund Koch

Proceedings Volume 7889, 788909 (2011) https://doi.org/10.1117/12.874636

KEYWORDS: Optical coherence tomography, Retina, Eye, Tissue optics, Image quality, Retinal scanning, In vivo imaging, Eye models, Optic nerve, Head

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SPIE Journal Paper | 1 July 2010 Open Access

Signal power decrease due to fringe washout as an extension of the limited Doppler flow measurement range in spectral domain optical coherence tomography

Julia Walther, Gregor Mueller, Henning Morawietz, Edmund Koch

JBO, Vol. 15, Issue 04, 041511, (July 2010) https://doi.org/10.1117/12.10.1117/1.3466578

KEYWORDS: Doppler effect, Optical coherence tomography, Phase shifts, Blood circulation, Doppler tomography, In vivo imaging, Capillaries, Motion models, Arteries, Solids

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Proceedings Article | 20 February 2010 Paper

The role of a detector dead time in phase-resolved Doppler analysis using spectral domain optical coherence tomography

Julia Walther, Peter Cimalla, Edmund Koch

Proceedings Volume 7554, 75542B (2010) https://doi.org/10.1117/12.839467

KEYWORDS: Sensors, Phase shifts, Optical coherence tomography, Doppler tomography, Doppler effect, Statistical modeling, Capillaries, Statistical analysis, Spectroscopy, Motion models

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Proceedings Article | 20 February 2010 Paper

Minimal invasive localization of the germinal disc in ovo for subsequent chicken sexing using optical coherence tomography

Anke Burkhardt, Stefan Geissler, Peter Cimalla, Julia Walther, Edmund Koch

Proceedings Volume 7554, 75542N (2010) https://doi.org/10.1117/12.839463

KEYWORDS: Optical coherence tomography, Head, Optical scanning, Magnetic resonance imaging, Scanners, Ultrasonography, Computed tomography, Tissue optics, 3D scanning, Image resolution

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Proceedings Article | 13 February 2010 Paper

Investigations of the intravascular backscattering distribution of light in optical coherence tomography

Peter Cimalla, Julia Walther, Edmund Koch

Proceedings Volume 7554, 755406 (2010) https://doi.org/10.1117/12.841947

KEYWORDS: Optical coherence tomography, Blood, Modulation, Arteries, Backscatter, Blood vessels, Heart, Data modeling, Glasses, In vivo imaging

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