Dr. Raghavan Rajagopalan Profile

Dr. Raghavan Rajagopalan

Principal Research Scientist at Mallinckrodt Pharmaceuticals

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Author

Publications (17)

Proceedings Article | 21 February 2013 Paper

Real-time point-of-care measurement of impaired renal function in a rat acute injury model employing exogenous fluorescent tracer agents

Richard Dorshow, Richard Fitch, Karen Galen, Jolette Wojdyla, Amruta Poreddy, John Freskos, Raghavan Rajagopalan, Jeng-Jong Shieh, Sevag Demirjian

Proceedings Volume 8596, 85960Z (2013) https://doi.org/10.1117/12.2003078

KEYWORDS: Kidney, Injuries, Plasma, Biomedical optics, Point-of-care devices, Skin, Fiber optics, Systems modeling, In vivo imaging, Analog electronics

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Proceedings Article | 12 February 2011 Paper

Development of fluorescent tracers for the real-time monitoring of renal function

Amruta Poreddy, Bethel Asmelash, Martin Debreczeny, Richard Fitch, John Freskos, Karen Galen, Kimberly Gaston, James Kostelc, Rana Kumar, Tim Marzan, William Neumann, Raghavan Rajagopalan, Tasha Schoenstein, Jeng-Jong Shieh, J. Micah Wilcox, Jolette Wojdyla, Richard Dorshow

Proceedings Volume 7910, 791010 (2011) https://doi.org/10.1117/12.874917

KEYWORDS: Analog electronics, Plasma, In vivo imaging, Proteins, Molecules, Lead, Tissue optics, Luminescence, Blood, In vitro testing

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Proceedings Article | 8 February 2011 Paper

Folate receptor targeted Type 1 photosensitizer bioconjugates for tumor visualization and phototherapy

Raghavan Rajagopalan, Amruta Poreddy, Amolkumar Karwa, Bethel Asmelash, Nicole Putnam, Lori Chinen, Maureen Nichols, J. Jeng Shieh, Richard Dorshow

Proceedings Volume 7886, 78860D (2011) https://doi.org/10.1117/12.875166

KEYWORDS: Receptors, Photosensitizer targeting, Confocal microscopy, Cancer, Sensors, Tumors, Ovarian cancer, Photodynamic therapy, Phototherapy, In vitro testing

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Proceedings Article | 3 March 2010 Paper

Novel visible light activated type 1 photosensitizers

Raghavan Rajagopalan, Amolkumar Karwa, Amruta Poreddy, Przemyslaw Lusiak, Raghoottama Pandurangi, Gary Cantrell, Richard Dorshow

Proceedings Volume 7551, 75510R (2010) https://doi.org/10.1117/12.844970

KEYWORDS: Visible radiation, Photodynamic therapy, Leukemia, Oxygen, Control systems, Tumors, Phototherapy, Cell death, Ultraviolet radiation, In vitro testing

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Proceedings Article | 3 March 2010 Paper

In vitro biological effects of novel type I photosensitizers and their mechanism of action

Amolkumar Karwa, Raghavan Rajagopalan, Amruta Poreddy, Carolyn Sympson, Gary Cantrell, Richard Dorshow

Proceedings Volume 7551, 75510S (2010) https://doi.org/10.1117/12.844971

KEYWORDS: Cell death, Ultraviolet radiation, Oxygen, Photodynamic therapy, In vitro testing, Phototherapy, Luminescence, Chemistry, Lamps, Visible radiation

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Proceedings Article | 13 July 2009 Paper

Novel type 1 photosensitizers: viability of leukemia cells exposed to reactive intermediates generated in situ by in vitro photofragmentation

Raghavan Rajagopalan, Amol Karwa, Przemyslaw Lusiak, Kripa Srivastava, Amruta Poreddy, Raghootama Pandurangi, Karen Galen, William Neumann, Gary Cantrell, Richard Dorshow

Proceedings Volume 7380, 738027 (2009) https://doi.org/10.1117/12.822840

KEYWORDS: Leukemia, Photodynamic therapy, In vitro testing, Oxygen, Cell death, Tumors, Photosensitizer targeting, Phototherapy, Control systems, Ultraviolet radiation

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Proceedings Article | 21 February 2009 Paper

N-alkylated aminopyrazines for use as hydrophilic optical agents

Amruta Poreddy, Bethel Asmelash, Karen Galen, Richard Fitch, Jeng-Jong Shieh, James Wilcox, Tasha Schoenstein, Jolette Wojdyla, Kimberly Gaston, John Freskos, William Neumann, Raghavan Rajagopalan, Hyo-Yang Ahn, James Kostelc, Martin Debreczeny, Kevin Belfield, Richard Dorshow

Proceedings Volume 7190, 71900P (2009) https://doi.org/10.1117/12.809287

KEYWORDS: Plasma, Luminescence, Proteins, Absorption, Tissue optics, In vivo imaging, Molecules, Ear, Kidney, Blood

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Proceedings Article | 22 February 2008 Paper

Fluorescence-enhanced europium complexes for the assessment of renal function

Lori Chinen, Karen Galen, K. Kuan, Mary Dyszlewski, Hiroaki Ozaki, Hiroaki Sawai, Raghootama Pandurangi, Frederick Jacobs, Richard Dorshow, Raghavan Rajagopalan

Proceedings Volume 6867, 68670B (2008) https://doi.org/10.1117/12.763665

KEYWORDS: Europium, Luminescence, Metals, Kidney, Fluorescence resonance energy transfer, Tissues, Antennas, Blood, Forward error correction, Liver

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Proceedings Article | 22 February 2008 Paper

New optical probes for continuous monitoring of renal function

Richard Dorshow, Bethel Asmelash, Lori Chinen, Martin Debreczeny, Richard Fitch, John Freskos, Karen Galen, Kimberly Gaston, Timothy Marzan, Amruta Poreddy, Raghavan Rajagopalan, Jeng-Jong Shieh, William Neumann

Proceedings Volume 6867, 68670C (2008) https://doi.org/10.1117/12.763697

KEYWORDS: Plasma, Luminescence, Proteins, Molecules, In vivo imaging, Blood, Ear, Fluorescence spectroscopy, Synthetic aperture radar, Veins

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Proceedings Article | 4 April 2005 Paper

Unexpected long-term stability of a cyanine dye bioconjugate

Richard Dorshow, Raghavan Rajagopalan

Proceedings Volume 5704, (2005) https://doi.org/10.1117/12.590506

KEYWORDS: Blood, Luminescence, Tumors, Near infrared, Optical imaging, Glasses, Charge-coupled devices, Receptors, In vivo imaging, Fluorescence spectroscopy

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Proceedings Article | 2 July 2001 Paper

New approach to optical imaging of tumors

Samuel Achilefu, Joseph Bugaj, Richard Dorshow, Hermo Jimenez, Raghavan Rajagopalan

Proceedings Volume 4259, (2001) https://doi.org/10.1117/12.432489

KEYWORDS: Tumors, Receptors, In vivo imaging, Optical imaging, Tissues, Luminescence, Solids, Molecules, Animal model studies, Tumor growth modeling

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Proceedings Article | 2 July 2001 Paper

Targeted Type 1 phototherapeutic agents using azido-peptide bioconjugates

Raghavan Rajagopalan, Samuel Achilefu, Hermo Jimenez, Elizabeth Webb, Michelle Schmidt, Joseph Bugaj, Richard Dorshow

Proceedings Volume 4259, (2001) https://doi.org/10.1117/12.432494

KEYWORDS: Receptors, Tissue optics, Phototherapy, Oxygen, Tumors, Energy transfer, Solids, Near infrared, Lung cancer, Tissues

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SPIE Journal Paper | 1 April 2001 Open Access

Novel fluorescent contrast agents for optical imaging of in vivo tumors based on a receptor-targeted dye-peptide conjugate platform

Joseph Bugaj, Samuel Achilefu, Richard Dorshow, Raghavan Rajagopalan

JBO, Vol. 6, Issue 02, (April 2001) https://doi.org/10.1117/12.10.1117/1.1352748

KEYWORDS: Tumors, Receptors, Luminescence, Tissues, In vivo imaging, Optical imaging, Solids, Tissue optics, Liver, Animal model studies

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Proceedings Article | 31 January 2001 Paper

Site-specific tumor-targeted fluorescent contrast agents

Samuel Achilefu, Joseph Bugaj, Richard Dorshow, Hermo Jimenez, Raghavan Rajagopalan, R. Randy Wilhelm, Elizabeth Webb, Jack Erion

Proceedings Volume 4156, (2001) https://doi.org/10.1117/12.413736

KEYWORDS: Tumors, Receptors, Tissues, In vivo imaging, Solids, Luminescence, In vitro testing, Molecules, Cancer, Blood

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Proceedings Article | 26 April 2000 Paper

Polyionic fluorescent bioconjugates as tracer agents for continuous monitoring of renal function

Raghavan Rajagopalan, Joseph Bugaj, Richard Dorshow, C. Venkatramani, Pamela Uetrecht, Samuel Achilefu

Proceedings Volume 3924, (2000) https://doi.org/10.1117/12.384250

KEYWORDS: Blood, Sodium, Molecules, Micro optical fluidics, Kidney, Chlorine, Time metrology, Medium wave, Luminescence, Liver

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Proceedings Article | 19 April 2000 Paper

Tumor-specific fluorescent contrast agents

Samuel Achilefu, Richard Dorshow, Joseph Bugaj, Raghavan Rajagopalan

Proceedings Volume 3917, (2000) https://doi.org/10.1117/12.382718

KEYWORDS: Tumors, Receptors, Solids, In vivo imaging, Liver, Luminescence, Tissues, Inflammation, Target detection, Optical imaging

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Proceedings Article | 17 May 1999 Paper

Monitoring physiological function by detection of exogenous fluorescent contrast agents

Richard Dorshow, Joseph Bugaj, Samuel Achilefu, Raghavan Rajagopalan, Arthur Combs

Proceedings Volume 3599, (1999) https://doi.org/10.1117/12.348383

KEYWORDS: Luminescence, Fiber optics, Fluorescence spectroscopy, Blood, Ear, In vivo imaging, Veins, In vitro testing, Chlorine, Indocyanine green

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Showing 5 of 17 publications

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