Mr. Robert C. Ike Profile

Robert C. Ike

SPIE Involvement:

Author

Publications (1)

This will count as one of your downloads.

You will have access to both the presentation and article (if available).

DOWNLOAD NOW

This content is available for download via your institution's subscription. To access this item, please sign in to your personal account.

Email or Username Forgot your username?

Password Forgot your password?

Show

Keep me signed in

No SPIE account? Create an account

Proceedings Article | 17 March 2008 Paper

Effect of ROI size on the performance of an information-theoretic CAD system in mammography: multi-size fusion analysis

Robert Ike, Swatee Singh, Brian Harrawood, Georgia Tourassi

Proceedings Volume 6915, 691527 (2008) https://doi.org/10.1117/12.772678

KEYWORDS: CAD systems, Mammography, Computer aided design, Databases, Computer aided diagnosis and therapy, Statistical analysis, Digital mammography, Breast, Image fusion, Solid modeling

Read Abstract +

Featureless, knowledge-based CAD systems are an attractive alternative to feature-based CAD because they require no to minimal image preprocessing. Such systems compare images directly using the raw image pixel values rather than relying on low-level image features. Specifically, information-theoretic (IT) measures such as mutual information (MI) have been shown to be an effective, featureless, similarity measure for image comparisons. MI captures the statistical relationship between the gray level values of corresponding image pixels. In a CAD system developed at our laboratory, the above concept has been applied for location-specific detection of mammographic masses. The system is designed to operate on a fixed size region of interest (ROI) extracted around a suspicious mammographic location. Since mass sizes vary substantially, there is a potential drawback. When two ROIs are compared, it is unclear how much the parenchymal background contributes in the calculated MI. This uncertainty could deteriorate CAD performance in the extreme cases, namely when a small mass is present in the ROI or when a large mass extends beyond the fixed size ROI. The present study evaluates the effect of ROI size on the overall CAD performance and proposes multisize analysis for possible improvement. Based on two datasets of ROIs extracted from DDSM mammograms, there was a statistically significant decline of the CAD performance as the ROI size increased. The best size ranged between 512x512 and 256x256 pixels. Multisize fusion analysis using a linear model achieved further improvement in CAD performance for both datasets.

My Library

You currently do not have any folders to save your paper to! Create a new folder below.

Folder Name

Folder Description

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks. You are receiving this notice because your organization may not have SPIE eBooks access.*

*Shibboleth/Open Athens users─please sign in to access your institution's subscriptions.

To obtain this item, you may purchase the complete book in print or electronic format on SPIE.org.

ORGANIZATIONAL
Sign in with credentials provided by your organization.

Organizational Username

Organizational Password

Show/Hide Password

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

;

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members:

Non-members: ADD TO CART

Keywords/Phrases

Search In:

Publication Years