A lens-less optical fiber designed for enhanced-fluorescence biosensor applications is presented. In order to obtain the enhanced sensor performances, two elements are essential: a planar antenna that redirects fluorescence emission into a narrow cone and an automated fiber-based optical system for multi-spot analysis. In particular, the potential early diagnosis of sepsis via C-reactive protein (CRP) detection is here demonstrated, reaching a limit of detection of 1.5 ng/mL), which is in the clinical range of interest for such biomarker. Upon the combination with other sepsis biomarkers, the presented sensor can become relevant for the early diagnosis of sepsis. These results validate the developed prototype as a simple, affordable, easy-to-operate, plug&play device with fast turnaround times, compatible with standardized micro-well arrays, and potentially suitable for POC applications with respect to the diagnosis of sepsis. It is also suitable for implementation with other biomarkers and liquid environments.
The latest progresses in polaritonic solar devices, in which molecular absorbers and photon modes of a resonator are hybridized as a result of strong coupling regime, have revealed that light-matter interaction can be an interesting tool to control and enhance devices performances. In this talk, light harvesting properties of broadband absorbers operating under weak, strong and ultra-strong coupling regimes are discussed. The spectral and directional response, together with the effect of polaritons on unproductive absorption due to the presence of metallic films in the structure are discussed in detail. These results allow to establish the optimum configuration to exploit the potential of solar cells devised as optical resonators.
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