In this paper, beam-shifting optical coherence tomography (BSOCT) is presented for speckle reduction and flow rate measurement. The sample beam is rotated about the optical axis of the objective lens to modulate the incident angle on sample; 17 and 3 incident angles are respectively performed for speckle reduction and flow rate measurement. The performance of the proposed technique is investigated on both phantom and in vivo experiments. By combining a 2D micro-electro-mechanical system (MEMS) and a zigzag scanning protocol, the frame rates of 45.2 Hz for speckle reduction and 25.6 Hz for flow rate measurement are achieved. With beam-shifting angle of 4.76º, the speckle noise reduction of 91% and the flow rate measurement precision of 0.0019 μl/s are achieved.
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