Plasma medicine: past, present, and future

Michael Keidar

doi:10.1117/12.3004224

13 March 2024 Plasma medicine: past, present, and future

Michael Keidar

Proceedings Volume PC12843, Biophotonics and Immune Responses XIX; PC128430C (2024) https://doi.org/10.1117/12.3004224
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Intense research effort in low-temperature (or cold) atmospheric plasma application in bioengineering led to foundation of a new field, plasma medicine. Cold atmospheric plasmas (CAP) produce chemically reactive species including reactive oxygen species (ROS) and reactive nitrogen species (RNS). These species are known to have biological effects on prokaryotic and eukaryotic cells, such as the peroxidation of lipids and proteins. The most recent research area of plasma medicine is the interaction of CAP with cancer cells. It has been demonstrated by several investigators that CAP can induce apoptosis (programmed cell death) in various cancer cell lines. In addition, CAP treatment affects preferentially the cell cycle of cancer cells. This opened up the possibility that CAP could be the basis of a new cancer therapy. The uniqueness of low-temperature plasma is in its ability to change composition in situ. The above mentioned biomedical applications seem to usher a new transformational approach to healthcare based on CAP technology. In this presentation a review of the research achievements accomplished in the last decade will be presented.

Conference Presentation

Citation Download Citation

Michael Keidar "Plasma medicine: past, present, and future", Proc. SPIE PC12843, Biophotonics and Immune Responses XIX, PC128430C (13 March 2024); https://doi.org/10.1117/12.3004224

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