1National Renewable Energy Lab. (United States) 2Institute for Quantum Science and Technology (United States) 3Institute for Quantum Science and Technology, Texas A&M Univ. (United States)
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
Stimulated Raman scattering (SRS) microscopy using picosecond near-IR pulses has provided a great penetration depth with reduced fluorescence interference when imaging biological samples for bioenergy applications. These tools have provided insight into 1) tracking the degradation of chemical composites in biomass feedstocks to investigate the recalcitrant factors during the deconstruction processes, 2) monitoring the production of chemicals in photosynthetic plants and wood-digesting microorganisms, and 3) probing plant-bacteria interactions. However, the above processes are usually slow and require continuous imaging for an extended period. This is challenging for classic SRS because the laser power needed to achieve enough sensitivity causes photodamage in the samples during such long experiments. Quantum-squeezed light with reduced noise in the intensity quadrature can improve the sensitivity of classic SRS microscopy beyond the shot noise limit. The successful squeezing of one of the picosecond pulses in the above SRS will improve sensitivity and reduce photodamage, greatly expanding the range of studies available to SRS microscopy.
Yining Zeng,Zhenhuan Yi,Girish Agarwal,Marlan Scully, andBryon Donohoe
"Squeezed light stimulated Raman scattering (SRS) microscopy for bioenergy applications", Proc. SPIE PC12855, Advanced Chemical Microscopy for Life Science and Translational Medicine 2024, PC1285502 (13 March 2024); https://doi.org/10.1117/12.3014634
ACCESS THE FULL ARTICLE
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
The alert did not successfully save. Please try again later.
Yining Zeng, Zhenhuan Yi, Girish Agarwal, Marlan Scully, Bryon Donohoe, "Squeezed light stimulated Raman scattering (SRS) microscopy for bioenergy applications," Proc. SPIE PC12855, Advanced Chemical Microscopy for Life Science and Translational Medicine 2024, PC1285502 (13 March 2024); https://doi.org/10.1117/12.3014634