Paper
31 October 2016 In vivo hyperspectral imaging and differentiation of skin cancer
Larisa A. Zherdeva, Ivan A. Bratchenko, Oleg O. Myakinin, Alexander A. Moryatov, Sergey V. Kozlov, Valery P. Zakharov
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Abstract
Results of hyperspectral imaging analysis for in vivo visualization of skin neoplasms are presented. 16 melanomas, 19 basal cell carcinomas and 10 benign tumors with different stages of neoplasm growth were tested. The HSI system provide skin tissue images with 5 nm spectral resolution in the range of 450-750 nm with automatic stabilization of each frame compensating displacement of the scanning area due to spontaneous macro-movements of the patient. The integrated optical densities in 530-600 and 600-670 nm ranges are used for real-time hemoglobin and melanin distribution imaging in skin tissue. It was shown that the total accuracy of skin cancer identification exceeds 90% and 70% for differentiation of melanomas from BCC and begihn tumors. It was demonstrated the possibility for HSI classification of melanomas of different stages.
© (2016) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Larisa A. Zherdeva, Ivan A. Bratchenko, Oleg O. Myakinin, Alexander A. Moryatov, Sergey V. Kozlov, and Valery P. Zakharov "In vivo hyperspectral imaging and differentiation of skin cancer", Proc. SPIE 10024, Optics in Health Care and Biomedical Optics VII, 100244G (31 October 2016); https://doi.org/10.1117/12.2246433
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Cited by 9 scholarly publications.
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KEYWORDS
Tumors

Skin

Cancer

In vivo imaging

Melanoma

Skin cancer

Hyperspectral imaging

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