Towards non-invasive high-resolution 3D nano-tomography by ultrasonic scanning probe microscopy

Hossein J. Sharahi; Gajendra Shekhawat; Vinayak Dravid; Philip Egberts; Seonghwan Kim

doi:10.1117/12.2269817

12 July 2017 Towards non-invasive high-resolution 3D nano-tomography by ultrasonic scanning probe microscopy

Hossein J. Sharahi, Gajendra Shekhawat, Vinayak Dravid, Philip Egberts, Seonghwan Kim

Proceedings Volume 10324, International Conference on Nano-Bio Sensing, Imaging, and Spectroscopy 2017; 1032408 (2017) https://doi.org/10.1117/12.2269817
Event: International Conference on Nano-Bio Sensing, Imaging, and Spectroscopy 2017, 2017, Jeju, Korea, Republic of

Abstract

Nanoscale imaging techniques that can be used to visualize and characterize local aggregations of the embedded nanoparticulates with sufficient resolution have attracted a great deal of interest. Ultrasonic scanning probe microscopy (SPM) and its derivatives are nondestructive techniques that can be used to elucidate subsurface nanoscale features and mechanical properties. Although many different ultrasonic methods have been used for subsurface imaging, the mechanisms and crucial parameters associated with the contrast formation in subsurface imaging are still unclear. Here, the impact of mechanical properties of the nanoparticulates/matrix, size of the nanoparticulates, buried depth of the nanoparticulates, and the ultrasonic excitation frequency on the developed ultrasonic SPM images have been investigated. To verify our theoretical model, experimental measurements of scanning near-field ultrasound holography (SNFUH) have been recreated in our theoretical analysis to reveal comparable variations in phase contrast measured in SNFUH while scanning over the nanoparticulates embedded in bacteria.

Citation Download Citation

Hossein J. Sharahi, Gajendra Shekhawat, Vinayak Dravid, Philip Egberts, and Seonghwan Kim "Towards non-invasive high-resolution 3D nano-tomography by ultrasonic scanning probe microscopy", Proc. SPIE 10324, International Conference on Nano-Bio Sensing, Imaging, and Spectroscopy 2017, 1032408 (12 July 2017); https://doi.org/10.1117/12.2269817

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available