Temperature feedback-controlled photothermal treatment based on thermal infrared imager

Haibin Chen; Dezi Li; Zhifang Li

doi:10.1117/12.2507579

7 March 2019 Temperature feedback-controlled photothermal treatment based on thermal infrared imager

Haibin Chen, Dezi Li, Zhifang Li

Proceedings Volume 10879, Biophotonics and Immune Responses XIV; 108790T (2019) https://doi.org/10.1117/12.2507579
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

To minimize thermal injury, the temperature monitoring with a proportional-integrative-derivative (PID) controller was applied for photothermal treatment of tumors. The thermocouple was used to estimate the temperature. However, it is impossible for thermocouple to measure the spatio-temporal developments of the temperature in tissue. In this work, we present temperature feedback-controlled photothermal treatment based on thermal infrared imager. Experiments demonstrated comparable thermal behaviors in temperature distribution and the degree of irreversible tissue denaturation for the different PID-controlled applications. Integration of temperature feedback with thermal infrared imager-assisted photothermal treatments can provide a feasible therapeutic modality to treat tumors in an effective manner.

Citation Download Citation

Haibin Chen, Dezi Li, and Zhifang Li "Temperature feedback-controlled photothermal treatment based on thermal infrared imager", Proc. SPIE 10879, Biophotonics and Immune Responses XIV, 108790T (7 March 2019); https://doi.org/10.1117/12.2507579

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