Optical fine-needle biopsy approach for intraoperative multimodal diagnostics in minimally invasive abdominal surgery

Ksenia Kandurova; Elena Potapova; Valery Shupletsov; Igor Kozlov; Evgeniya Seryogina; Viktor Dremin; Evgeny Zherebtsov; Alexander Alekseyev M.D.; Andrian Mamoshin M.D.; Andrey Dunaev

doi:10.1117/12.2526747

22 July 2019 Optical fine-needle biopsy approach for intraoperative multimodal diagnostics in minimally invasive abdominal surgery

Ksenia Kandurova, Elena Potapova, Valery Shupletsov, Igor Kozlov, Evgeniya Seryogina, Viktor Dremin, Evgeny Zherebtsov, Alexander Alekseyev M.D., Andrian Mamoshin M.D., Andrey Dunaev

Author Affiliations +

Proceedings Volume 11079, Medical Laser Applications and Laser-Tissue Interactions IX; 110791C (2019) https://doi.org/10.1117/12.2526747
Event: European Conferences on Biomedical Optics, 2019, Munich, Germany

Abstract

The paper describes the methodology and technical implementation of a multimodal approach for optical diagnostics in hepatopancreatobiliary organs focal and diffuse neoplasms. Fine needle aspiration biopsy technique and following cytological examination show its effectiveness and safety but its performing takes several days. However, the problem of real-time analysis of pathological changes in tissues remains relevant. The solution suggested is implementing of optical biopsy methods (namely fluorescence spectroscopy and diffuse reflectance spectroscopy) in the form of fiber-optic probe compatible with standard biopsy fine needles. The special device was designed for this purpose to conduct optical measurements and compare the results with ones obtained by conventional biopsy. The proposed methodology seems promising for developing new diagnostic criteria for clinical practice.

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Ksenia Kandurova, Elena Potapova, Valery Shupletsov, Igor Kozlov, Evgeniya Seryogina, Viktor Dremin, Evgeny Zherebtsov, Alexander Alekseyev M.D., Andrian Mamoshin M.D., and Andrey Dunaev "Optical fine-needle biopsy approach for intraoperative multimodal diagnostics in minimally invasive abdominal surgery", Proc. SPIE 11079, Medical Laser Applications and Laser-Tissue Interactions IX, 110791C (22 July 2019); https://doi.org/10.1117/12.2526747

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