Spatial coordinate corrected motion tracking for optical coherence elastography

Xuan Liu; Yuwei Liu; Basil Hubbi; Xianlian Zhou; Stephen Peters

doi:10.1117/12.2546070

13 February 2020 Spatial coordinate corrected motion tracking for optical coherence elastography

Xuan Liu, Yuwei Liu, Basil Hubbi, Xianlian Zhou, Stephen Peters

Proceedings Volume 11242, Optical Elastography and Tissue Biomechanics VII; 1124218 (2020) https://doi.org/10.1117/12.2546070
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

We develop a spatial coordinate corrected (SCC) motion tracking method for optical coherence elastography. SCC motion tracking refers the instantaneous velocity field extracted from optical coherence tomography (OCT) data to the laboratory coordinate system and accurately reconstructs the displacement field established during the mechanical excitation (compression) process. We acquired image data from compression OCE experiments on human breast tissue specimens, and reconstructed the displacement field through Doppler analysis of OCT data. Our results suggested that SCC tracking enables accurate reconstruction of displacement field, and enables effective identification mechanical heterogeneity that can be used as a biomarker for cancer diagnosis and tumor margin assessment.

Citation Download Citation

Xuan Liu, Yuwei Liu, Basil Hubbi, Xianlian Zhou, and Stephen Peters "Spatial coordinate corrected motion tracking for optical coherence elastography", Proc. SPIE 11242, Optical Elastography and Tissue Biomechanics VII, 1124218 (13 February 2020); https://doi.org/10.1117/12.2546070

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