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10 March 2020 High throughput screening of cancer cells using holographic cytometry (Conference Presentation)
Han Sang Park, Will J. Eldridge, Silvia Ceballos, Adam P. Wax
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Proceedings Volume 11251, Label-free Biomedical Imaging and Sensing (LBIS) 2020; 1125121 (2020) https://doi.org/10.1117/12.2546157
Event: SPIE BiOS, 2020, San Francisco, California, United States
Abstract
In order to advance quantitative phase microscopy as a significant clinical tool, we have implemented a new modality, holographic cytometry, which provides high resolution phase maps at high frame rates using several novel advances such as high speed line scan cameras integrated with microfluidic and illuminated with pulsed light source. The system is used to examine carcinogenic changes in epithelial cells which have been exposed to heavy metals in population sizes that are diagnostically relevant.
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Han Sang Park, Will J. Eldridge, Silvia Ceballos, and Adam P. Wax "High throughput screening of cancer cells using holographic cytometry (Conference Presentation)", Proc. SPIE 11251, Label-free Biomedical Imaging and Sensing (LBIS) 2020, 1125121 (10 March 2020); https://doi.org/10.1117/12.2546157
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KEYWORDS
Holography
Cancer
Image segmentation
Image resolution
Imaging systems
Line scan cameras
Microfluidics
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