Development of simulations for a mesh-based x-ray phase imaging system

Laila Hassan; Weiyuan Sun; Carolyn A. MacDonald; Jonathan C. Petruccelli

doi:10.1117/12.2549358

16 March 2020 Development of simulations for a mesh-based x-ray phase imaging system

Laila Hassan, Weiyuan Sun, Carolyn A. MacDonald, Jonathan C. Petruccelli

Proceedings Volume 11312, Medical Imaging 2020: Physics of Medical Imaging; 1131253 (2020) https://doi.org/10.1117/12.2549358
Event: SPIE Medical Imaging, 2020, Houston, Texas, United States

Abstract

X-ray phase imaging can significantly improve image contrast in soft-tissue imaging applications such as mammography where the inherent contrast in conventional attenuation-based imaging is low. A system that employs a stainless steel wire mesh to produce a high-contrast structured illumination pattern reduces the need for source coherence and complex alignments. Phase is reconstructed from distortions in this pattern due to phase-based x-ray deflection. A computational model of this system has been developed that allows exploration of design parameters including source size, mesh period, sample structure, detector pixel size and locations of these system elements. Simulation results are presented and compared with experiment for validation.

Citation Download Citation

Laila Hassan, Weiyuan Sun, Carolyn A. MacDonald, and Jonathan C. Petruccelli "Development of simulations for a mesh-based x-ray phase imaging system", Proc. SPIE 11312, Medical Imaging 2020: Physics of Medical Imaging, 1131253 (16 March 2020); https://doi.org/10.1117/12.2549358

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