Development And Performance Of A Novel IR-ATR-Based Glucose Sensor System

Ch. Weigel; R. Kellner

doi:10.1117/12.969392

1 December 1989 Development And Performance Of A Novel IR-ATR-Based Glucose Sensor System

Ch. Weigel, R. Kellner

Proceedings Volume 1145, 7th Intl Conf on Fourier Transform Spectroscopy; (1989) https://doi.org/10.1117/12.969392
Event: Seventh International Conference on Fourier and Computerized Infrared Spectroscopy, 1989, Fairfax, VA, United States

Abstract

FTIR-ATR-spectroscopy can be used to design an optical glucose sensing system. The building of an immobilized enzyme layer, via 3-Aminopropyltriethoxysilane (3-APTS) and glutaraldehyde leads to a stable glucose oxidase (GOD) film on a germanium crystal with a thickness smeller than the penetration depth of the IR-radiation (<0.5 um). The system measures the absorbance of the 1153 cm gluconic acid band and exhibits a good linearity (for glucose concentrations of 0.52 - 20 mM) with a correlation coefficient of 0.96.

Citation Download Citation

Ch. Weigel and R. Kellner "Development And Performance Of A Novel IR-ATR-Based Glucose Sensor System", Proc. SPIE 1145, 7th Intl Conf on Fourier Transform Spectroscopy, (1 December 1989); https://doi.org/10.1117/12.969392

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