Plasmon enhanced upconversion in water-dispersible nanostructures

Kyuyoung Bae; Ananda Das; Wounjhang Park

doi:10.1117/12.2568802

21 August 2020 Plasmon enhanced upconversion in water-dispersible nanostructures

Kyuyoung Bae, Ananda Das, Wounjhang Park

Proceedings Volume 11467, Nanoengineering: Fabrication, Properties, Optics, Thin Films, and Devices XVII; 1146714 (2020) https://doi.org/10.1117/12.2568802
Event: SPIE Nanoscience + Engineering, 2020, Online Only

Abstract

Upconversion materials have attracted much interest for biomedical applications. However, a wide-spread use requires a much improved upconversion efficiency for which plasmonic nanostructures offer a highly promising route. This paper presents the latest development in plasmonic nanostructures coupled with upconversion nanoparticles (UCNPs). First, a demonstration of over 1000x enhancement using a metal-insulator-metal architecture will be presented. Additionally, UCNP-gold nanostructure was conjugated with antibody to epidermal growth factor to target bladder cancer cells. We have demonstrated highly selective cell killing by optoporation-aided chemotherapy.

Conference Presentation

Citation Download Citation

Kyuyoung Bae, Ananda Das, and Wounjhang Park "Plasmon enhanced upconversion in water-dispersible nanostructures", Proc. SPIE 11467, Nanoengineering: Fabrication, Properties, Optics, Thin Films, and Devices XVII, 1146714 (21 August 2020); https://doi.org/10.1117/12.2568802

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