Image quality assessment for closed-loop computer-assisted lung ultrasound

Zachary M. C. Baum; Ester Bonmati; Lorenzo Cristoni; Andrew Walden; Ferran Prados; Baris Kanber; Dean C. Barratt; David J. Hawkes; Geoff J. M. Parker; Claudia A. M. Gandini Wheeler-Kingshott; Yipeng Hu

doi:10.1117/12.2581865

15 February 2021 Image quality assessment for closed-loop computer-assisted lung ultrasound

Zachary M. C. Baum, Ester Bonmati, Lorenzo Cristoni, Andrew Walden, Ferran Prados, Baris Kanber, Dean C. Barratt, David J. Hawkes, Geoff J. M. Parker, Claudia A. M. Gandini Wheeler-Kingshott, Yipeng Hu

Author Affiliations +

Proceedings Volume 11598, Medical Imaging 2021: Image-Guided Procedures, Robotic Interventions, and Modeling; 115980R (2021) https://doi.org/10.1117/12.2581865
Event: SPIE Medical Imaging, 2021, Online Only

Abstract

We describe a novel, two-stage computer assistance system for lung anomaly detection using ultrasound imaging in the intensive care setting to improve operator performance and patient stratification during coronavirus pandemics. The proposed system consists of two deep-learning-based models: a quality assessment module that automates predictions of image quality, and a diagnosis assistance module that determines the likelihood-of-anomaly in ultrasound images of sufficient quality. Our two-stage strategy uses a novelty detection algorithm to address the lack of control cases available for training the quality assessment classifier. The diagnosis assistance module can then be trained with data that are deemed of sufficient quality, guaranteed by the closed-loop feedback mechanism from the quality assessment module. Using more than 25,000 ultrasound images from 37 COVID-19-positive patients scanned at two hospitals, plus 12 control cases, this study demonstrates the feasibility of using the proposed machine learning approach. We report an accuracy of 86% when classifying between sufficient and insufficient quality images by the quality assessment module. For data of sufficient quality – as determined by the quality assessment module – the mean classification accuracy, sensitivity, and specificity in detecting COVID-19-positive cases were 0.95, 0.91, and 0.97, respectively, across five holdout test data sets unseen during the training of any networks within the proposed system. Overall, the integration of the two modules yields accurate, fast, and practical acquisition guidance and diagnostic assistance for patients with suspected respiratory conditions at pointof- care.

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Zachary M. C. Baum, Ester Bonmati, Lorenzo Cristoni, Andrew Walden, Ferran Prados, Baris Kanber, Dean C. Barratt, David J. Hawkes, Geoff J. M. Parker, Claudia A. M. Gandini Wheeler-Kingshott, and Yipeng Hu "Image quality assessment for closed-loop computer-assisted lung ultrasound", Proc. SPIE 11598, Medical Imaging 2021: Image-Guided Procedures, Robotic Interventions, and Modeling, 115980R (15 February 2021); https://doi.org/10.1117/12.2581865

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