Diffuse optical spectroscopy from bench to bedside to wearable to implant

Thomas D. O'Sullivan

doi:10.1117/12.2590878

5 March 2021 Diffuse optical spectroscopy from bench to bedside to wearable to implant

Thomas D. O'Sullivan

Proceedings Volume 11622, Multiscale Imaging and Spectroscopy II; 116220J (2021) https://doi.org/10.1117/12.2590878
Event: SPIE BiOS, 2021, Online Only

Abstract

Diffuse optical spectroscopy (DOS), also known as near-infrared spectroscopy (NIRS), offers sub-micromolar sensitivity to tissue composition, perfusion, and oxygen metabolism; low patient risk since DOS requires neither ionizing radiation nor contrast agents; and relatively low-cost instrumentation. Consequently, DOS methods are applied in virtually all major areas of clinical research including neurologic disease, cancer, cardiovascular disease, metabolic disease, and trauma/critical care. Compared to other medical imaging technologies, DOS allows for ultracompact integration that can enable handheld, wearable, and even implanted DOS-based sensing strategies. In this presentation, we discuss our work to create a handheld frequency-domain quantitative tissue imager and a tumor-implantable DOS-based sensor roughly the size of a standard breast radiological clip.

Conference Presentation

Citation Download Citation

Thomas D. O'Sullivan "Diffuse optical spectroscopy from bench to bedside to wearable to implant", Proc. SPIE 11622, Multiscale Imaging and Spectroscopy II, 116220J (5 March 2021); https://doi.org/10.1117/12.2590878

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