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5 March 2021 In vivo delineation of human carotid plaque structure and composition by Acoustic Radiation Force Impulse (ARFI) ultrasound
Caterina M. Gallippi, Gabriela Torres, Jonathon W. Homeister, Mark A. Farber, Melissa C. Caughey
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Proceedings Volume 11645, Optical Elastography and Tissue Biomechanics VIII; 116450U (2021) https://doi.org/10.1117/12.2578273
Event: SPIE BiOS, 2021, Online Only
Abstract
Acoustic Radiation Force Impulse (ARFI) imaging employs sound impulses to induce and track tissue motion that conveys mechanical property. In application to carotid atherosclerotic plaque, ARFI noninvasively delineates features that convey risk for ischemic stroke: intraplaque hemorrhage, lipid-rich necrotic core, thin or ruptured fibrous cap, diffuse collagen, and calcium deposits. This talk will feature recent advances to in vivo ARFI atherosclerosis imaging technology, including the use of machine learning for automated feature classification, which are validated histologically in patients undergoing carotid endarterectomy. New developments, including incorporating vector blood flow estimation for combined shear strain assessment, will be highlighted.
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Caterina M. Gallippi, Gabriela Torres, Jonathon W. Homeister, Mark A. Farber, and Melissa C. Caughey "In vivo delineation of human carotid plaque structure and composition by Acoustic Radiation Force Impulse (ARFI) ultrasound", Proc. SPIE 11645, Optical Elastography and Tissue Biomechanics VIII, 116450U (5 March 2021); https://doi.org/10.1117/12.2578273
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KEYWORDS
In vivo imaging
Acoustics
Ultrasonography
Data acquisition
Tissues
Blood circulation
Calcium
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