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Optical diffraction tomography (ODT) as a kind of label-free three-dimensional imaging technique has been widely used in biomedical imaging. To decrease the volume of ODT instrumentation and broaden the applications of the ODT technique, we propose a novel design to achieve a miniaturized ODT system based on using a vertical-cavity surface-emitting laser (VCSEL) array and a self-interference unit. In our proposed system design, a dome-shaped VCSEL array is used to generate angle scanning illuminations, and the self-interference unit is applied to record the off-axis interferograms from different illumination angles. We have verified the accuracy of phase retrieval of our system and investigated the proper illumination angles and reconstruction model for further system development.
Haojia Sun andRenjie Zhou
"Miniaturization of an optical diffraction tomography system", Proc. SPIE 11653, Quantitative Phase Imaging VII, 116531M (5 March 2021); https://doi.org/10.1117/12.2583386
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