GPC-modalities for neurophotonics and optogenetics

Jesper Glückstad; René L. Eriksen; Andreas Gejl Madsen

doi:10.1117/12.2583507

5 March 2021 GPC-modalities for neurophotonics and optogenetics

Jesper Glückstad, René L. Eriksen, Andreas Gejl Madsen

Proceedings Volume 11701, Complex Light and Optical Forces XV; 117011D (2021) https://doi.org/10.1117/12.2583507
Event: SPIE OPTO, 2021, Online Only

Abstract

The powerful discipline of optogenetics can be described as “the branch of biotechnology which combines genetic engineering with optics to observe and control the function of genetically targeted groups of cells with light”. Using advanced laser beam-shaping such as Generalized Phase Contrast (GPC) and derived holographic modalities makes it possible to take advantage of cutting-edge two-photon technology to develop an unprecedented ‘circuit optogenetics’ platform with both high spatio-temporal selectivity and high penetration depth without disturbing speckle-noise. We will report on the latest laser shaping GPC-modalities with temporal focusing to uniquely sculpt patterns of one- and two-photon excitations for living neural-circuits and genetically modified light-sensitive cells.

Conference Presentation

Citation Download Citation

Jesper Glückstad, René L. Eriksen, and Andreas Gejl Madsen "GPC-modalities for neurophotonics and optogenetics", Proc. SPIE 11701, Complex Light and Optical Forces XV, 117011D (5 March 2021); https://doi.org/10.1117/12.2583507

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available