The gene "N" encodes the nucleocapsid structural protein of SARS–CoV-2 virus COVID-19. In the present time, nucleocapsid protein is one of the important targets for the study of both humoral and cellular immune responses to SARS–CoV-2. In this study sequence of the SARS-CoV-2 gene "N", which is encoding the relevant structural protein, has been transformed into the sequence of numbers with purpose to generate gene-based speckles. Differences in the initial nucleotide sequences have been found and characterized by means of virtual laser gene-based speckles (GBspeckles). It has been shown, that at the interference of two SARS–CoV-2 GB-speckle-patterns, two types of interference pictures are forming: quasi-random speckle structure without interference fringes or fringes, modulated by speckles. It has been demonstrated that implication of interference of two GB-speckles, generated on the virus nucleotide sequences, can be considered as a new direction in modern bioinformatics.
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