Two-wavelength excitation spectroscopy for non-invasive detection of the iron deficiency indicator zinc protoporphyrin IX

Herbert Stepp; Christian Homann; Georg Hennig; Michael Vogeser

doi:10.1117/12.2614588

7 December 2021 Two-wavelength excitation spectroscopy for non-invasive detection of the iron deficiency indicator zinc protoporphyrin IX

Herbert Stepp, Christian Homann, Georg Hennig, Michael Vogeser

Author Affiliations +

Proceedings Volume 11919, Translational Biophotonics: Diagnostics and Therapeutics; 119190O (2021) https://doi.org/10.1117/12.2614588
Event: European Conferences on Biomedical Optics, 2021, Online Only

Abstract

Increased formation of fluorescent zinc protoporphyrin IX (ZnPP) inside erythrocytes indicates functional iron deficiency. Two-wavelength excitation spectroscopy detects ZnPP even through intact skin. Its suitability was successfully tested in women, surgical patients, infants and blood donors.

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Herbert Stepp, Christian Homann, Georg Hennig, and Michael Vogeser "Two-wavelength excitation spectroscopy for non-invasive detection of the iron deficiency indicator zinc protoporphyrin IX", Proc. SPIE 11919, Translational Biophotonics: Diagnostics and Therapeutics, 119190O (7 December 2021); https://doi.org/10.1117/12.2614588

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