Survival from melanoma, the deadliest form of skin cancer, depends heavily on early detection. Several non-invasive medical imaging modalities have been developed to detect melanoma, of which optical coherence tomography (OCT) is gaining popularity. Although OCT generally does not yet provide sufficient performance in detecting melanoma, radiomic studies involving quantitative OCT image analysis demonstrate promising results. We propose extracting a large set of radiomic features from OCT images of skin, exploring how the features differ between melanoma and non-melanoma, and performing feature selection to identify the most informative OCT radiomic features that characterize melanoma for improved melanoma detection.
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