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Optical coherence tomography (OCT) with a robust depth-resolved attenuation compensation method for a wide range of imaging applications is proposed and demonstrated. We derive a model for deducing the attenuation coefficients and the signal compensation value using the depth-dependent backscattering profiles, to mitigate under and overestimation in tissue imaging. We validated the method using numerical simulation and phantoms, where we achieved stable and robust compensation results over the entire depth of samples. The comparison between other attenuation characterization models and our proposed model is also performed.
Yaning Wang,Shuwen Wei, andJin U. Kang
"Depth-resolved backscattering signal reconstruction based OCT attenuation compensation", Proc. SPIE 11953, Optical Fibers and Sensors for Medical Diagnostics, Treatment and Environmental Applications XXII, 119530D (2 March 2022); https://doi.org/10.1117/12.2609114
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Yaning Wang, Shuwen Wei, Jin U. Kang, "Depth-resolved backscattering signal reconstruction based OCT attenuation compensation," Proc. SPIE 11953, Optical Fibers and Sensors for Medical Diagnostics, Treatment and Environmental Applications XXII, 119530D (2 March 2022); https://doi.org/10.1117/12.2609114