A speculum free portable preterm imaging system

Tananant Boonya-Ananta; Mariacarla Gonzalez; Vinh Nguyen Du Le; Edward DeHoog; Michael J. Paidas; Arumugam Jayakumar; Jessica C. Ramella-Roman

doi:10.1117/12.2609915

4 March 2022 A speculum free portable preterm imaging system

Tananant Boonya-Ananta, Mariacarla Gonzalez, Vinh Nguyen Du Le, Edward DeHoog, Michael J. Paidas, Arumugam Jayakumar, Jessica C. Ramella-Roman

Author Affiliations +

Proceedings Volume 11963, Polarized Light and Optical Angular Momentum for Biomedical Diagnostics 2022; 119630A (2022) https://doi.org/10.1117/12.2609915
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Preterm birth (PTB) is defined as any birth prior to 37 weeks of gestation. Preterm birth contributes to 35% of 3.1 million neonatal deaths annually. There is a critical absence of clinical tools for diagnosis of preterm birth risk. We have proposed the use of Mueller Matrix Imaging (MMI) as a sensitive tool to monitor the atypical remodeling of collagen occurring in PTB. Here we expand our previous work to demonstrate that a Portable PReterm IMaging System capable of 3x4 MMI can be used at the point of care. It consists of a sheath insertable in the vaginal canal combined with a polarized imaging system. The main PPRIM body consists of a camera with integrated polarizers combined with a custom-made LED ring illuminator. The optical layout consists of a reverse telephoto lens suitable for imaging at long front working distance. Angle of incidence of the optical elements are minimized to reduce the sensitivity to misalignment and polarization aberrations. The system has a field of view of approximately 25 x 25 mm² at 20 mm working distance. PPRIM is controlled by a laptop computer and custom software. To demonstrate the feasibility of the device, imaging tests were performed on a Gynecologic Skills Trainer as well as healthy volunteers.

Citation Download Citation

Tananant Boonya-Ananta, Mariacarla Gonzalez, Vinh Nguyen Du Le, Edward DeHoog, Michael J. Paidas, Arumugam Jayakumar, and Jessica C. Ramella-Roman "A speculum free portable preterm imaging system", Proc. SPIE 11963, Polarized Light and Optical Angular Momentum for Biomedical Diagnostics 2022, 119630A (4 March 2022); https://doi.org/10.1117/12.2609915

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KEYWORDS

Imaging systems

Cervix

Cameras

Computer aided design

Optical components

Polarization

In vivo imaging

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