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Cord blood collected from the umbilical cord differs from human adult blood in many aspects and haematological properties. Viscosity and surface tension of adult blood is higher than that of cord whole blood. Therefore, in the present study, Adult blood-RBC and Cord blood-RBC were optically trapped using an Optical Tweezer. The Optical Tweezer consists of laser of λ=975 nm with 100 mW maximum power and quadrant photodetector (QPD) based force measurement system. Power spectrum density (PSD), cut off frequency (fc) and optical force calculation for both the types of RBC showed significant differences. RBC folding and unfolding time which is an indicator of RBC rigidity was measured for both Adult and Cord blood-RBC.
Sarika Hinge,A. G. Banpurkar, andG. R. Kulkarni
"Optical trapping of cord blood and adult blood: RBC", Proc. SPIE 11964, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XX, 119640B (3 March 2022); https://doi.org/10.1117/12.2609509
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Sarika Hinge, A. G. Banpurkar, G. R. Kulkarni, "Optical trapping of cord blood and adult blood: RBC," Proc. SPIE 11964, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XX, 119640B (3 March 2022); https://doi.org/10.1117/12.2609509