Evaluating procedures for establishing generative adversarial network-based stochastic image models in medical imaging

Varun A. Kelkar; Dimitrios S. Gotsis; Frank J. Brooks; Kyle J. Myers; Prabhat K.C.; Rongping Zeng; Mark A. Anastasio

doi:10.1117/12.2612893

4 April 2022 Evaluating procedures for establishing generative adversarial network-based stochastic image models in medical imaging

Varun A. Kelkar, Dimitrios S. Gotsis, Frank J. Brooks, Kyle J. Myers, Prabhat K.C., Rongping Zeng, Mark A. Anastasio

Author Affiliations +

Proceedings Volume 12035, Medical Imaging 2022: Image Perception, Observer Performance, and Technology Assessment; 120350O (2022) https://doi.org/10.1117/12.2612893
Event: SPIE Medical Imaging, 2022, San Diego, California, United States

Abstract

Modern generative models, such as generative adversarial networks (GANs), hold tremendous promise for several areas of medical imaging, such as unconditional medical image synthesis, image restoration, reconstruction and translation, and optimization of imaging systems. However, procedures for establishing stochastic image models (SIMs) using GANs remain generic and do not address specific issues relevant to medical imaging. In this work, canonical SIMs that simulate realistic vessels in angiography images are employed to evaluate procedures for establishing SIMs using GANs. The GAN-based SIM is compared to the canonical SIM based on its ability to reproduce those statistics that are meaningful to the particular medically realistic SIM considered. It is shown that evaluating GANs using classical metrics and medically relevant metrics may lead to different conclusions about the fidelity of the trained GANs. This work highlights the need for the development of objective metrics for evaluating GANs.

Conference Presentation

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Varun A. Kelkar, Dimitrios S. Gotsis, Frank J. Brooks, Kyle J. Myers, Prabhat K.C., Rongping Zeng, and Mark A. Anastasio "Evaluating procedures for establishing generative adversarial network-based stochastic image models in medical imaging", Proc. SPIE 12035, Medical Imaging 2022: Image Perception, Observer Performance, and Technology Assessment, 120350O (4 April 2022); https://doi.org/10.1117/12.2612893

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