Time resolved SPAD micro-camera probe for wide-field FLIm in microendoscopy

Dario Angelone; Sanathana Konugolu Venkata Sekar; Walter Messina; Andrew Matheson; Ahmet T. Erdogan; Robert K Henderson; Ray Burke; Stefan Andersson-Engels

doi:10.1117/12.2648340

6 March 2023 Time resolved SPAD micro-camera probe for wide-field FLIm in microendoscopy

Dario Angelone, Sanathana Konugolu Venkata Sekar, Walter Messina, Andrew Matheson, Ahmet T. Erdogan, Robert K Henderson, Ray Burke, Stefan Andersson-Engels

Author Affiliations +

Proceedings Volume 12368, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XXI; 1236807 (2023) https://doi.org/10.1117/12.2648340
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

We propose a handheld single photon avalanche diode (SPAD) micro-camera probe for wide-field in-vivo fluorescence lifetime imaging (FLIm) applications. The presented probe includes a novel 3D stacked 1.4 mm × 1.4 mm SPAD array, an integrated excitation light source, and imaging optics. The spatial and temporal performance of the integrated system was characterised using a USAF test target and range of fluorescence lifetime beads.

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Citation Download Citation

Dario Angelone, Sanathana Konugolu Venkata Sekar, Walter Messina, Andrew Matheson, Ahmet T. Erdogan, Robert K Henderson, Ray Burke, and Stefan Andersson-Engels "Time resolved SPAD micro-camera probe for wide-field FLIm in microendoscopy", Proc. SPIE 12368, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XXI, 1236807 (6 March 2023); https://doi.org/10.1117/12.2648340

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