Partial Mueller polarimetry for the complete optical diagnosis of biological tissue

Tatiana Novikova; Jessica C. Ramella-Roman; Leonard Felger; Romain Gros; Ekkehard Hewer; Theoni Maragkou; Richard McKinley; Stefano Moriconi; Michael Murek; Angelo Pierangelo; Omar Rodríguez-Núñez; Irena Zubak; Philippe Schucht

doi:10.1117/12.2670094

11 August 2023 Partial Mueller polarimetry for the complete optical diagnosis of biological tissue

Tatiana Novikova, Jessica C. Ramella-Roman, Leonard Felger, Romain Gros, Ekkehard Hewer, Theoni Maragkou, Richard McKinley, Stefano Moriconi, Michael Murek, Angelo Pierangelo, Omar Rodríguez-Núñez, Irena Zubak, Philippe Schucht

Author Affiliations +

Proceedings Volume 12629, Emerging Technologies for Cell and Tissue Characterization II; 1262902 (2023) https://doi.org/10.1117/12.2670094
Event: European Conferences on Biomedical Optics, 2023, Munich, Germany

Abstract

Imaging Mueller polarimetry has already proved its potential for biomedical applications. However, tissue characterization utilizing all 16 elements of the Mueller matrix (MM) is not straightforward and requires data postprocessing decomposition algorithms. We developed the theoretical framework and performed the experimental studies on extracting the polarimetric parameters of phantoms and biological tissue while using only part of MM elements and validating them against the results of Lu-Chipman decomposition of corresponding complete MMs. Our findings open an avenue for developing simple and compact polarimetric systems operating at video rates that can be translated to clinics for real-time tissue diagnosis and monitoring.

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Tatiana Novikova, Jessica C. Ramella-Roman, Leonard Felger, Romain Gros, Ekkehard Hewer, Theoni Maragkou, Richard McKinley, Stefano Moriconi, Michael Murek, Angelo Pierangelo, Omar Rodríguez-Núñez, Irena Zubak, and Philippe Schucht "Partial Mueller polarimetry for the complete optical diagnosis of biological tissue", Proc. SPIE 12629, Emerging Technologies for Cell and Tissue Characterization II, 1262902 (11 August 2023); https://doi.org/10.1117/12.2670094

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KEYWORDS

Polarimetry

Tissues

Biomedical optics

Mueller matrices

Tissue optics

Depolarization

Polarization

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