Imaging capillary details with spectrally extended line field optical coherence tomography angiography

Si Chen; Kan Lin; Xi Chen; Linbo Liu

doi:10.1117/12.2670010

11 August 2023 Imaging capillary details with spectrally extended line field optical coherence tomography angiography

Si Chen, Kan Lin, Xi Chen, Linbo Liu

Proceedings Volume 12632, Optical Coherence Imaging Techniques and Imaging in Scattering Media V; 126321K (2023) https://doi.org/10.1117/12.2670010
Event: European Conferences on Biomedical Optics, 2023, Munich, Germany

Abstract

Optical Coherence Tomography Angiography (OCTA), a functional extension of Optical Coherence Tomography (OCT), is capable of imaging blood flow signals non-invasively at the capillary level without the need for dye injection. However, widespread usage of OCTA is hindered by the trade-off between transverse sampling rate and Signal to Noise Ratio (SNR). To achieve a clinically applicable field of view, capillary fine details are commonly sacrificed due to under-sampling. In addition, the image contrast of capillaries suffers from 'thin line' motion artifacts. We introduce spectrally extended line field OCTA (SELF-OCTA) that tackles the above-mentioned issues with parallel transverse sampling and increased allowable light exposure. We show that SELF-OCTA provides significantly improved sampling density and image contrast for microvasculature compared with the standard OCTA technique.

Citation Download Citation

Si Chen, Kan Lin, Xi Chen, and Linbo Liu "Imaging capillary details with spectrally extended line field optical coherence tomography angiography", Proc. SPIE 12632, Optical Coherence Imaging Techniques and Imaging in Scattering Media V, 126321K (11 August 2023); https://doi.org/10.1117/12.2670010

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KEYWORDS

Capillaries

Optical coherence tomography

Angiography

Sampling rates

Signal to noise ratio

Spatial frequencies

Heart

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