Rapid detection of synthetic cannabinoids via fluorescence spectral fingerprints

R. Kumar; Gyles E. Cozier; Rachael C. Andrews; Christopher R. Pudney

doi:10.1117/12.2685133

5 October 2023 Rapid detection of synthetic cannabinoids via fluorescence spectral fingerprints

R. Kumar, Gyles E. Cozier, Rachael C. Andrews, Christopher R. Pudney

Proceedings Volume 12652, UV and Higher Energy Photonics: From Materials to Applications 2023; 1265208 (2023) https://doi.org/10.1117/12.2685133
Event: SPIE Nanoscience + Engineering, 2023, San Diego, California, United States

Abstract

Synthetic Cannabinoids (SCs), also known as "Spice", are a category of Schedule 1 drugs consisting of over 200 chemically diverse compounds. They are prevalent in UK prisons and homeless groups often sold on a range of matrices (herbal, paper and fabric) and at unknown concentrations. To reduce the harm these drugs cause, rapid and accurate detection is required. Due to their chemical diversity, detection can be challenging. Their identification can be achieved using spectroscopic approaches such as LCQTOF-MS, LC-MS-MS, GC-MS, NMR, and ATR-IR. However, these are time-consuming and laboratory-intensive, requiring advanced training. Recently, we provided evidence that excitation-emission matrices can be used to ‘fingerprint the presence of SCs’ which we call a fluorescence spectral fingerprint (FSF). Here we demonstrate a portable device, based-on an array of LEDs as excitation sources, that can produce FSFs that are of sufficiently high resolution to discriminate FSFs of individual SCs.

Conference Presentation

(2023) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

R. Kumar, Gyles E. Cozier, Rachael C. Andrews, and Christopher R. Pudney "Rapid detection of synthetic cannabinoids via fluorescence spectral fingerprints", Proc. SPIE 12652, UV and Higher Energy Photonics: From Materials to Applications 2023, 1265208 (5 October 2023); https://doi.org/10.1117/12.2685133

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