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Imaging techniques with subdiffraction-limited spatial resolutions are highly desired for a deeper understanding of subcellular systems. Optical imaging enables high resolution under 200 nm while the visible light penetration depth is limited to merely 2 mm. Ultrasound images achieve two orders of magnitude lower resolutions but can penetrate two orders of magnitude deeper into a medium than optical images. This work combines the strengths of optical and acoustic imaging techniques through AuNP-based metasurfaces utilizing the photoacoustic effect that gold exhibits. Our novel imaging technique can simultaneously achieve high resolution and deep penetration depths without any destruction of media.
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Jiuk Byun, Julia Holland, Tamal Roy, Zaid Haddadin, Nicholas Boechler, Lisa V. Poulikakos, "Photoacoustic metasurface design with gold nanoparticles (AuNPs) for dynamic acoustic wavefront shaping," Proc. SPIE 12693, Unconventional Imaging, Sensing, and Adaptive Optics 2023, 126931A (4 October 2023); https://doi.org/10.1117/12.2677822