Research progress of circRNA and its role in the development of colorectal cancer

Jingwen Chen

doi:10.1117/12.3000273

7 September 2023 Research progress of circRNA and its role in the development of colorectal cancer

Jingwen Chen

Proceedings Volume 12789, International Conference on Modern Medicine and Global Health (ICMMGH 2023); 127891O (2023) https://doi.org/10.1117/12.3000273
Event: International Conference on Modern Medicine and Global Health (ICMMGH 2023), 2023, Oxford, United Kingdom

Abstract

Circular RNA (circRNA) is one kind of non-coding RNA. It is characterized with closed circular structure without 5' or 3' end and poly A tail. CircRNAs affect biological function by binding with miRNA and other molecules at the transcriptional or post transcriptional level. The latest research progress shows that circRNAs have an obvious influence on the physiological activities of colorectal cancer cells, including proliferation, metastasis and apoptosis. These activities are closely concerned with the development and prognosis of colorectal cancer (CRC). This paper makes a summary on the role of circRNAs in the development of CRC and assesses their possibility to work as therapeutic targets and biomarkers.

(2023) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Jingwen Chen "Research progress of circRNA and its role in the development of colorectal cancer", Proc. SPIE 12789, International Conference on Modern Medicine and Global Health (ICMMGH 2023), 127891O (7 September 2023); https://doi.org/10.1117/12.3000273

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