High-frequency terahertz waves regulate the dynamic network of mitochondria in neuropathic pain model of mice

Yuchen Tian; Wenyu Peng

doi:10.1117/12.3016597

18 June 2024 High-frequency terahertz waves regulate the dynamic network of mitochondria in neuropathic pain model of mice

Yuchen Tian, Wenyu Peng

Author Affiliations +

Proceedings Volume 12994, Terahertz Photonics III; 129940A (2024) https://doi.org/10.1117/12.3016597
Event: SPIE Photonics Europe, 2024, Strasbourg, France

Abstract

High-frequency Terahertz waves, operating at the level of molecular group vibrations, hold promise in regulating the function of biomolecules and potentially interfering with the progression of associated diseases. In this research, we established a neuropathic pain (NP) mice model using spared nerve injury (SNI) and observed that a frequency of approximately 36 THz could alleviate NP. Furthermore, we noted that this frequency can regulated the mitochondrial dynamic network in the anterior cingulate cortex (ACC) region, leading to enhanced ATP production. This article tries to explore the potential mechanism between high-frequency terahertz waves and NP through mitochondria, which may be a promising strategy for the therapy of other mitochondria diseases.

Conference Presentation

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Yuchen Tian and Wenyu Peng "High-frequency terahertz waves regulate the dynamic network of mitochondria in neuropathic pain model of mice", Proc. SPIE 12994, Terahertz Photonics III, 129940A (18 June 2024); https://doi.org/10.1117/12.3016597

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