Measurement of blood hematocrit by dual-wavelength near-IR photoplethysmography

Joseph M. Schmitt; Guan-Xiong Zhou; Justin Miller

doi:10.1117/12.59360

6 May 1992 Measurement of blood hematocrit by dual-wavelength near-IR photoplethysmography

Joseph M. Schmitt, Guan-Xiong Zhou, Justin Miller

Proceedings Volume 1641, Physiological Monitoring and Early Detection Diagnostic Methods; (1992) https://doi.org/10.1117/12.59360
Event: OE/LASE '92, 1992, Los Angeles, CA, United States

Abstract

Blood hematocrit is routinely determined in the clinic by analysis of blood samples. This paper introduces an non-invasive method for measuring arterial blood hematocrit which, when combined with pulse oximetry, potentially enables simultaneous monitoring of hemoglobin concentration and oxygen saturation. It is based on the same principles underlying pulse oximetry, except two light sources that emit close to isobestic wavelengths of oxy/deoxyhemoglobin in the near-infrared band (800 nm and 1300 nm) are employed. Hematocrjt is related to the ratios of the pulsatile and nonpulsatile components of the diffuse intensity transmitted through a blood-perfused tissue at these wavelengths. To test the feasibility of the method, we developed an in vitro light-scattering model with optical properties similar to those of skin tissue. Measurements were made using semiconductor light sources and detectors. We discuss the experimental results in the context of theoretical predictions that show the effect of variations in the volume fraction of blood and water in tissue. Finally, potential problems concerning calibration in a clinical setting are addressed.

Citation Download Citation

Joseph M. Schmitt, Guan-Xiong Zhou, and Justin Miller "Measurement of blood hematocrit by dual-wavelength near-IR photoplethysmography", Proc. SPIE 1641, Physiological Monitoring and Early Detection Diagnostic Methods, (6 May 1992); https://doi.org/10.1117/12.59360

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