Morphological and functional effects of induced laser retinal fibrosis

Harry Zwick; Steven T. Schuschereba; Donald A. Gagliano; M. Silverman; David J. Lund; Scottie B. Reynolds; Bruce E. Stuck

doi:10.1117/12.168742

15 February 1994 Morphological and functional effects of induced laser retinal fibrosis

Harry Zwick, Steven T. Schuschereba, Donald A. Gagliano, M. Silverman, David J. Lund, Scottie B. Reynolds, Bruce E. Stuck

Author Affiliations +

Proceedings Volume 2079, Laser Applications in Ophthalmology; (1994) https://doi.org/10.1117/12.168742
Event: Europto Biomedical Optics '93, 1993, Budapest, Hungary

Abstract

Human laser accident exposure cases may involve severe macula retinal injury resulting in long term visual acuity and spatial vision deficit. In order to investigate this problem, we have chosen to model the effects of such long term exposure in the monkey retina for parafoveal Q- switched exposure produced at two parafoveal exposure sites. Our results suggest significant loss of retinal function in and adjacent to the scar region. Recovery occurs in regions with less scar formation, the foveal region, although long term changes in foveal receptor mechanisms are apparent even after 1 year post-exposure, they do not correlate completely with recent human investigations of severe accidental exposure nor with brain enzyme analysis in our monkey model.

Citation Download Citation

Harry Zwick, Steven T. Schuschereba, Donald A. Gagliano, M. Silverman, David J. Lund, Scottie B. Reynolds, and Bruce E. Stuck "Morphological and functional effects of induced laser retinal fibrosis", Proc. SPIE 2079, Laser Applications in Ophthalmology, (15 February 1994); https://doi.org/10.1117/12.168742

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