Fourier transform infrared spectroscopic studies on DNA polymorphism

W. P. Pohle; Hartmut Fritzsche

doi:10.1117/12.166674

31 January 1994 Fourier transform infrared spectroscopic studies on DNA polymorphism

W. P. Pohle, Hartmut Fritzsche

Proceedings Volume 2089, 9th International Conference on Fourier Transform Spectroscopy; (1994) https://doi.org/10.1117/12.166674
Event: Fourier Transform Spectroscopy: Ninth International Conference, 1993, Calgary, Canada

Abstract

DNA as a biopolymeric molecule standing directly in the center of the molecular biological processing in the cell exhibits a pronounced polymorphism. Infrared spectroscopy (IRS) is a very suitable tool to perform conformational analyses of DNA especially when using its Fourier transform (FT) version and/or the linear dichroism (LD). Spectral features of the sugar-phosphate backbone and of the bases of DNA can be utilized to characterize aspects of DNA conformation as illustrated for the A and B forms and for the unusual parallel-stranded (ps) form of DNA, respectively.

Citation Download Citation

W. P. Pohle and Hartmut Fritzsche "Fourier transform infrared spectroscopic studies on DNA polymorphism", Proc. SPIE 2089, 9th International Conference on Fourier Transform Spectroscopy, (31 January 1994); https://doi.org/10.1117/12.166674

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available